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Long-term surgical outcomes of retinal detachment in patients with Stickler syndrome

机译：Stickler综合征患者视网膜脱离的长期手术结局

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Purpose: The aim of the study was to present the long-term anatomical and visual outcomes of retinal detachment repair in patients with Stickler syndrome. Patients and methods: This study is a retrospective, interventional, consecutive case series of patients with Stickler syndrome undergoing retinal reattachment surgery from 2009 to 2014 at the Associated Retinal Consultants, William Beaumont Hospital. Results: Sixteen eyes from 13 patients were identified. Patients underwent a mean of 3.1 surgical interventions (range: 1–13) with a mean postoperative follow-up of 94?months (range: 5–313?months). Twelve eyes (75%) developed proliferative vitreoretinopathy. Retinal reattachment was achieved in 100% of eyes, with ten eyes (63%) requiring silicone oil tamponade at final follow-up. Mean preoperative visual acuity (VA) was 20/914, which improved to 20/796 at final follow-up ( P =0.81). There was a significant correlation between presenting and final VA ( P <0.001), and patients with poorer presenting VA were more likely to require silicone oil tamponade at final follow-up ( P =0.04). Conclusion: Repair of retinal detachment in patients with Stickler syndrome often requires multiple surgeries, and visual outcomes are variable. Presenting VA is significantly predictive of long-term VA outcomes.
机译：目的：该研究的目的是介绍Stickler综合征患者视网膜脱离修复的长期解剖和视觉结果。患者和方法：本研究是2009年至2014年在William Beaumont医院相关视网膜顾问处接受视网膜复位手术的Stickler综合征患者的回顾性，连续性，连续病例系列。结果：从13例患者中鉴定出16眼。患者平均接受了3.1次外科手术（范围：1-13），术后平均随访时间为94个月（范围：5-313个月）。十二眼（75％）发展为增殖性玻璃体视网膜病变。视网膜重新附着达到100％的眼睛，在最后的随访中有十只眼睛（63％）需要硅油填塞。术前平均视力（VA）为20/914，在最终随访时提高至20/796（P = 0.81）。呈现VA和最终VA之间存在显着相关性（P <0.001），呈现VA较差的患者在最终随访时更有可能需要硅油填塞（P = 0.04）。结论：Stickler综合征患者的视网膜脱离修复通常需要多次手术，并且视觉结果是可变的。提出VA可以显着预测长期VA结局。

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