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首页> 外文期刊>Graefe's Archive for Clinical and Experimental Ophthalmology >Outcomes of surgery for retinal detachment in patients with Stickler syndrome: a comparison of two sequential 20-year cohorts
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Outcomes of surgery for retinal detachment in patients with Stickler syndrome: a comparison of two sequential 20-year cohorts

机译：Stickler综合征患者视网膜脱离的手术结果：连续两个20年队列的比较

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摘要

Stickler syndrome is a hereditary oculo-systemic disorder where patients are predisposed to retinal detachments which are often complex and challenging to manage. Significant progress has been made regarding the molecular genetics of the condition; however, there is little recent literature on surgery for retinal detachment in Stickler syndrome. Our aim is to describe a population of Stickler patients presenting to Moorfields Eye Hospital with detachment from 1986 to 2003. We looked at patient characteristics, characteristics of detachment, management and anatomical and functional outcomes. We also aim to compare this group from 1986 to 2003 with a past group of Stickler patients treated at Moorfields between 1965 and 1985, reported by (Billington et al. in Trans Ophthalmol Soc UK 104:875–879, 1985). This comparison of 20-year matched cohorts examined patient characteristics, features of detachment, management and anatomical outcome in the two groups using the same definitions as the earlier authors.
机译：斯蒂克勒综合征是一种遗传性眼球系统疾病，患者易患视网膜脱离，视网膜脱离通常很复杂且难以治疗。该病的分子遗传学已取得重大进展。然而，关于Stickler综合征视网膜脱离手术的最新文献很少。我们的目的是描述从1986年至2003年向Moorfields眼科医院就诊的Stickler患者人群。我们研究了患者的特征，脱离特征，处理以及解剖和功能结局。我们还打算将1986年至2003年的这一组患者与过去1965年至1985年在Moorfields接受治疗的Stickler患者组进行比较（Billington等在Trans Ophthalmol Soc UK 104：875-879，1985）中进行了报道。这项20年匹配队列的比较使用与早期作者相同的定义检查了两组患者的特征，脱离特征，处理和解剖结局。

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