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首页> 外文期刊>Clinical ophthalmology >360-degree suture trabeculotomy ab interno to treat open-angle glaucoma: 2-year outcomes
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360-degree suture trabeculotomy ab interno to treat open-angle glaucoma: 2-year outcomes

机译：360度缝线小梁切开术腹腔镜治疗开角型青光眼：2年预后

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Purpose: The purpose of this study was to evaluate the efficacy of 360-degree suture trabeculotomy (360S-LOT) ab interno for treating open-angle glaucoma (OAG). Risk factors of surgical failure were examined. Patients and methods: 360S-LOT ab interno alone was performed for patients with uncontrolled OAG, and combined 360S-LOT ab interno/phacoemulsification was performed for patients with controlled OAG with a visually significant cataract between March 2014 and September 2015 at a single center. The patients were prospectively followed for 2?years. The main outcome measures included 2-year intraocular pressure (IOP), number of anti-glaucoma medications used, postoperative complications, and predictive factors of surgical failure. Kaplan–Meier analysis was performed, with surgical success (with or without medication use) defined as postoperative IOP ≤15?mmHg and IOP reduction ≥20% (criterion A) or IOP ≤12?mmHg and IOP reduction ≥30% (criterion B). Predictive factors were evaluated using Cox proportional hazard ratios. Results: A total of 64 eyes of 64 patients were included, and 50 (78%) eyes of 64 eyes underwent a phacoemulsification combination procedure. Surgery significantly reduced IOP from 18.4 ± 2.9?mmHg before surgery to 13.4 ± 3.0?mmHg after surgery ( P < 0.001). Patients used an average of 1.8 ± 1.5 medications before surgery and 1.3 ± 1.5 medications after surgery ( P = 0.101). No serious postoperative complications were observed. The probability of surgical success was 49.2% and 16.0% using criteria A and B, respectively. No risk factors of surgical failure were identified. Conclusion: The 360S-LOT ab interno procedure is a favorable option for treating eyes with mild or moderate OAG.
机译：目的：本研究的目的是评估360度缝合小梁切开术（360S-LOT）ab interno治疗开角型青光眼（OAG）的疗效。检查了手术失败的危险因素。患者和方法：2014年3月至2015年9月之间，对单眼OAG不受控制的OAG患者单独进行360S-LOT腹腔镜检查，对OAG受控的OAG伴有明显视觉白内障的患者进行360S-LOT腹腔/超声乳化联合手术。对患者进行前瞻性随访2年。主要结局指标包括2年眼压（IOP），使用的抗青光眼药物的数量，术后并发症以及手术失败的预测因素。进行Kaplan–Meier分析，手术成功（有或无用药）定义为术后IOP≤15？mmHg，IOP降低≥20％（标准A）或IOP≤12？mmHg，IOP降低≥30％（标准B） ）。使用Cox比例风险比评估预测因素。结果：共纳入64例患者的64眼，并对64眼的50眼（78％）进行了超声乳化联合手术。手术使眼压从手术前的18.4±2.9？mmHg显着降低到手术后的13.4±3.0？mmHg（P <0.001）。患者术前平均使用1.8±1.5药物，术后平均1.3±1.5药物（P = 0.101）。没有观察到严重的术后并发症。使用标准A和标准B手术成功的可能性分别为49.2％和16.0％。没有发现手术失败的危险因素。结论：360S-LOT ab interno手术是治疗轻度或中度OAG眼的理想选择。

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