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首页> 外文期刊>Clinical ophthalmology >Visual evoked potential repeatability using the Diopsys NOVA LX fixed protocol in normal older adults
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Visual evoked potential repeatability using the Diopsys NOVA LX fixed protocol in normal older adults

机译：使用Diopsys NOVA LX固定协议在正常老年人中视觉诱发的潜在可重复性

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Purpose: The purpose of this study was to evaluate the intrasession and intersession repeatability of visual evoked potentials in normal adults over 40?years of age as recorded using the Diopsys NOVA LX fixed protocol. Methods: Inclusion criteria were adults aged over 40?years with best corrected distance acuity of 20/40 or better in each eye. Subjects underwent three consecutive visual evoked potential examinations using the Diopsys NOVA LX fixed protocol. All examination procedures were carried out in accordance with the manufacturer recommendations. To assess intersession repeatability, nine subjects returned in 2–6?weeks for repeat examination. Results: A total of 46 subjects were recruited. Mean ± SD age: 53±9?years (range: 40–84?years); 69% of subjects were female and 80% were non-white. Coefficients of variation (CVs) and intraclass correlation coefficients (ICCs) revealed greater repeatability for P100 latency (CV: 3%–7%; ICC: 0.39–0.76) than for P100 amplitude (CV: 21%–33%; ICC: 0.34–0.69) and greater repeatability for recordings made with high contrast stimuli (amplitude CV: 21%–23%; latency CV: 3%–7%) than low contrast stimuli (amplitude CV: 24%–33%; latency CV: 6%–7%). Minimum detectable change values ranged between 4.50 and 9.95 μv for amplitude and 8.16–15.26?ms for latency. Repeatability was not influenced by age, sex, or race. Conclusion: The Diopsys NOVA LX fixed protocol demonstrated clinically acceptable intrasession and intersession repeatability in these healthy older adults, with latency being more repeatable than amplitude and examinations employing high contrast stimuli being more repeatable than those using low contrast stimuli.
机译：目的：本研究的目的是评估使用Diopsys NOVA LX固定规程记录的40岁以上正常成年人的视觉诱发电位的闭会期间和闭会期间重复性。方法：纳入标准为40岁以上的成年人，每只眼睛的最佳矫正远视度为20/40或更高。使用Diopsys NOVA LX固定方案对受试者进行了三个连续的视觉诱发电位检查。所有检查程序均按照制造商的建议进行。为了评估休会期间的可重复性，有9位受试者在2-6周内返回进行重复检查。结果：共招募了46名受试者。平均±SD年龄：53±9？岁（范围：40–84？岁）; 69％的受试者为女性，80％为非白人。变异系数（CVs）和类内相关系数（ICCs）显示，P100潜伏期（CV：3％–7％; ICC：0.39–0.76）的重现性高于P100振幅（CV：21％–33％; ICC：0.34） –0.69）和高对比度刺激（振幅CV：21％–23％;潜伏期CV：3％–7％）录制的重复性高于低对比度刺激（振幅CV：24％–33％;潜伏期CV：6） ％–7％）。最小可检测变化值的幅度范围为4.50至9.95μv，延迟范围为8.16–15.26？ms。重复性不受年龄，性别或种族的影响。结论：Diopsys NOVA LX固定方案在这些健康的老年人中证明了临床上可接受的疗程内和疗程间重复性，其潜伏期比幅度重复性更高，并且使用高对比度刺激的检查比使用低对比度刺激的检查具有更高的重复性。

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