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首页> 外文期刊>Clinical ophthalmology >Surgery-induced iris abnormalities after Descemet membrane endothelial keratoplasty and their impact on postoperative clinical outcomes
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Surgery-induced iris abnormalities after Descemet membrane endothelial keratoplasty and their impact on postoperative clinical outcomes

机译：Descemet膜内皮角膜移植术后手术引起的虹膜异常及其对术后临床结局的影响

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Purpose: This study aimed to elucidate the frequency of surgery-induced iris abnormalities after Descemet membrane endothelial keratoplasty (DMEK) and their impact on postoperative clinical outcomes. Methods: In this retrospective study, medical records of 32 eyes from 28 consecutive patients (mean age, 65.7±13.4?years; 14 men, 18 women) who underwent DMEK (or triple DMEK) were reviewed. In all patients, inferior peripheral iridectomy was created leaving full intracameral air tamponade at the end of surgery. Sulfur hexafluoride gas was not used in any cases. Surgery-induced iris abnormalities such as pupillary shape changes and iris depigmentation were evaluated by 3 masked observers. Pre-existing abnormalities were excluded. Eyes were divided into two groups based on the presence of surgery-induced iris changes: Group A (with iris abnormalities) and Group B (without). Impacts on postoperative clinical outcomes such as vision and endothelial cell density were analyzed. Results: Surgery-induced iris abnormalities were seen in 15 eyes (Group A, 9 with pupillary shape change and 6 with iris depigmentation; 46.9%), and 17 eyes showed no abnormalities (Group B, 53.1%). No significant differences were detected between groups in age, sex, indication, simultaneous cataract surgery, pre- and 6-month postoperative vision, donor age, donor endothelial cell density, and 6- and 12-month postoperative endothelial cell density. Conclusions: Surgery-induced iris abnormalities were noted in almost half of the eyes after DMEK (46.9%) in this study. However, there was no association between visual outcomes or postoperative endothelial cell density and the iris changes.
机译：目的：本研究旨在阐明Descemet膜内皮角膜移植术（DMEK）后手术引起的虹膜异常的发生率及其对术后临床结局的影响。方法：在这项回顾性研究中，回顾了接受DMEK（或三重DMEK）治疗的28例连续患者（平均年龄65.7±13.4岁; 14例男性，18例女性）的32眼的病历。在所有患者中，均进行了下周边虹膜切除术，并在手术结束时留下了全部的前房内空气填塞。在任何情况下均不使用六氟化硫气体。由3名蒙面观察者评估了手术引起的虹膜异常，例如瞳孔形状变化和虹膜色素沉着。既往异常已排除。根据手术引起的虹膜变化，将眼睛分为两组：A组（虹膜异常）和B组（无虹膜异常）。分析了对视力和内皮细胞密度等术后临床结局的影响。结果：手术引起的虹膜异常观察到15只眼（A组，瞳孔形状​​改变为9只，虹膜色素沉着发生为6只，占46.9％），而17只眼未见异常（B组，占53.1％）。在年龄，性别，适应症，同时白内障手术，术后前和术后6个月的视力，供体年龄，供体内皮细胞密度以及术后6个月和12个月的内皮细胞密度之间，两组之间均未发现显着差异。结论：在这项研究中，手术诱发的虹膜异常在DMEK后几乎一半的眼睛中被发现（46.9％）。但是，视觉结果或术后内皮细胞密度与虹膜变化之间没有关联。

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