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Economic burden associated with chronic constipation in Sweden: a retrospective cohort study

机译:瑞典与慢性便秘相关的经济负担:一项回顾性队列研究

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Background: Chronic constipation is a common condition, but few studies have assessed its cost and impact on resource use. The purpose of this cohort study was to assess the health care utilization and costs of chronic constipation in a Swedish population using health care claims data. Methods: Data were compiled on health care costs, drug costs, and mortality for V?stra G?taland, Sweden (2005–2009). These data were used to identify patients aged 18 years or older with chronic constipation, defined as: at least two health care contacts with a primary diagnosis of constipation within 12 months or at least one care contact with a primary diagnosis of constipation and two dispatches of laxatives 6 months before and 12 months after the index date. Patients with irritable bowel syndrome or taking opioids, both of which can cause constipation, were excluded. Costs, resource use, comorbidities, and laxative use were assessed during a 12-month follow-up period. Results: In total, 4,043 patients with chronic constipation were identified. They had a mean (SD) age of 67±18 years. Mortality was 7% during the 12-month follow-up period and the most common comorbidity was hypertension (22%). In the 12-month follow-up period, patients with chronic constipation had a mean (SD) of 2.3±7.5 constipation-related health care contacts and a mean (SD) of 15.2±19.5 other health care contacts. Annual costs, adjusted for sex, age group, mortality, and comorbidities, were €5,388, of which €951 were for constipation-related care. Conclusion: Patients with chronic constipation constituted an elderly population with a high disease burden in Sweden between 2005 and 2009. Mean annual constipation-related health care costs, adjusted for potentially confounding factors, were €951 per patient.
机译:背景:慢性便秘是一种常见病,但很少有研究评估其成本和对资源使用的影响。这项队列研究的目的是使用医疗保健理赔数据评估瑞典人群的医疗保健利用率和慢性便秘的费用。方法:收集关于瑞典VästraGtaland的医疗保健成本,药物成本和死亡率的数据(2005-2009年)。这些数据用于识别18岁或以上的慢性便秘患者,定义为:至少两个在12个月内初步诊断为便秘的医疗保健联络人,或至少一次在初步诊断为便秘的医疗保健联络人中进行两次派发泻药在索引日期之前6个月和之后12个月。肠易激综合症或服用阿片类药物(均会引起便秘)被排除在外。在12个月的随访期内评估了成本,资源使用,合并症和泻药的使用。结果:总共确定了4,043例慢性便秘患者。他们的平均(SD)年龄为67±18岁。在12个月的随访期内,死亡率为7%,最常见的合并症是高血压(22%)。在12个月的随访期间,慢性便秘患者的平均(SD)为2.3±7.5,与便秘相关的医疗保健联系方式,平均(SD)为15.2±19.5。根据性别,年龄组,死亡率和合并症调整的年度费用为5,388欧元,其中951欧元用于便秘相关护理。结论:慢性便秘患者在2005年至2009年间构成瑞典的高疾病负担的老年人群。根据潜在的混杂因素调整后,与便秘相关的平均年医疗费用为每名患者€951。

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