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首页> 外文期刊>Clinical Pediatric Endocrinology >Treatment of Hypothyroidism due to Iodine Deficiency Using Daily Powdered Kelp in Patients Receiving Long-term Total Enteral Nutrition
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Treatment of Hypothyroidism due to Iodine Deficiency Using Daily Powdered Kelp in Patients Receiving Long-term Total Enteral Nutrition

机译：接受长期全肠内营养的患者每日使用海带粉治疗碘缺乏症引起的甲状腺功能减退

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摘要

We investigated thyroid function and urinary iodine concentration (UIC) in seven patients with severe motor intellectual disabilities. All seven received total enteral nutrition (TEN) for more than three years with a daily iodine intake of less than 20 μg. They were diagnosed as hypothyroidism due to iodine deficiency (HID) because of high TSH levels (7.6–82.3 μIU/ml), lower free T4 (FT4 0.4–1.5 ng/dl), negative anti-thyroid antibodies (anti-thyroglobulin antibody, anti-thyroidal peroxidase antibody) and extremely low UIC (<25–58 μg/l) levels. We gave them 1–2 g powdered kelp (200–400 μg as iodine) once a day, which restored their thyroid function and normalized their UICs. We proposed that daily powdered kelp would be effective and safe to treat HID in patient receiving long term TEN.
机译：我们调查了七名严重运动智力障碍患者的甲状腺功能和尿碘浓度（UIC）。所有七个人均接受了超过三年的总肠内营养（TEN），每日碘摄入量少于20μg。由于高TSH水平（7.6–82.3μIU/ ml），较低的游离T4（FT4 0.4–1.5 ng / dl），阴性的抗甲状腺抗体（抗甲状腺球蛋白抗体，抗甲状腺过氧化物酶抗体）和极低的UIC（<25–58μg/ l）水平。我们每天给他们1-2克海藻粉（200-400μg碘），可恢复其甲状腺功能并使UIC正常化。我们建议每日服用海带粉对长期接受TEN的患者治疗HID是有效和安全的。

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