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On the Tetraploid Origin of the Maize Genome

机译:玉米基因组的四倍体起源

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Data from cytological and genetic mapping studies suggest that maize arose asa tetraploid. Two previous studies investigating the most likely mode of maizeorigin arrived at different conclusions. Gaut and Doebley [7] proposed a segmentalallotetraploid origin of the maize genome and estimated that the two maizeprogenitors diverged at 20.5 million years ago (mya). In a similar study, using largerdata set, Brendel and colleagues (quoted in [8]) suggested a single genome duplicationat 16 mya. One of the key components of such analyses is to examine sequencedivergence among strictly orthologous genes. In order to identify such genes, Laiand colleagues [10] sequenced five duplicated chromosomal regions from the maizegenome and the orthologous counterparts from the sorghum genome. They alsoidentified the orthologous regions in rice. Using positional information of geneticcomponents, they identified 11 orthologous genes across the two duplicated regionsof maize, and the sorghum and rice regions. Swigonovaet al. [12] analyzed the 11orthologues, and showed that all five maize chromosomal regions duplicated at thesame time, supporting a tetraploid origin of maize, and that the two maize progenitorsdiverged from each other at about the same time as each of them diverged fromsorghum, about 11.9 mya.
机译:细胞学和遗传作图研究的数据表明,玉米是四倍体。先前的两个研究玉米ma的最可能模式的研究得出了不同的结论。 Gaut和Doebley [7]提出了玉米基因组的片段异源四倍体起源,并估计这两个玉米祖细胞在2050万年前(mya)发生了分歧。在一项类似的研究中,使用更大的数据集,Brendel及其同事(在[8]中引用)提出了在16 mya进行单基因组复制。此类分析的关键组成部分之一是检查严格直系同源基因之间的序列差异。为了鉴定此类基因,Laiand的同事[10]对来自玉米基因组的五个重复染色体区域和来自高粱基因组的直系同源序列进行了测序。他们还确定了水稻的直系同源区域。他们利用遗传成分的位置信息,在玉米的两个重复区域以及高粱和水稻区域中鉴定了11个直系同源基因。 Swigonovaet等。 [12]分析了11个同源基因,发现所有五个玉米染色体区域在同一时间重复,支持玉米的四倍体起源,并且两个玉米祖细胞在大约每个相同的时间从彼此的高粱中分离,大约为11.9。妙。

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