Ringtail in Suckling Munich Wistar Fromter Rats: A Histopathologic Study

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Ringtail in Suckling Munich Wistar Fromter Rats: A Histopathologic Study

机译：哺乳慕尼黑Wistar Fromter大鼠的环尾：组织病理学研究。

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Ringtailisapathologicconditionofthetailofratsandotherrodentsthatistraditionallyattributedtolowenvironmentalhumidity,althoughdietarydeficiencies,geneticsusceptibility,environmentaltemperature,anddegreeofhydrationoftheanimalalsohavebeensuggestedaspossiblecauses.Totheauthors'knowledge,adetailedhistopathologicstudythatmayservetoshedlightontheetiopathogenesisofthisdiseasehasnotyetbeenpublished.Wedescribethehistologicfindingsofringtailobservedin12sucklingMunichWistarFromter(MWF)ratsfromtwolitters.Epidermalhyperplasiacharacterizedbyorthokeratoticandparakeratotichyperkeratosisandacanthosiswasobservedinallaffectedrats.Numerousoftendilatedvesselswerepresentinthedermisoftailsthatappearedofred/browncoloratgrossexamination.Inseverecases,thedilatedvascularstructureswerethromboticandaccompaniedbydermalhemorrhagesandfocalcoagulativenecrosisoftheoverlyingepidermis.Thesefindingssuggestthatepidermalacanthosisandhyperkeratosisarethemainandprimaryeventsinthedevelopmentofringtail.Toclarifythecauseofthisdisease,futurestudiesshouldbefocusedonthenumerousfactorsthatcaninducesuchepidermalchanges.

机译：Ringtailisapathologicconditionofthetailofratsandotherrodentsthatistraditionallyattributedtolowenvironmentalhumidity，althoughdietarydeficiencies，geneticsusceptibility，environmentaltemperature，anddegreeofhydrationoftheanimalalsohavebeensuggestedaspossiblecauses.Totheauthors'knowledge，adetailedhistopathologicstudythatmayservetoshedlightontheetiopathogenesisofthisdiseasehasnotyetbeenpublished.Wedescribethehistologicfindingsofringtailobservedin12sucklingMunichWistarFromter（MWF）ratsfromtwolitters.Epidermalhyperplasiacharacterizedbyorthokeratoticandparakeratotichyperkeratosisandacanthosiswasobservedinallaffectedrats.Numerousoftendilatedvesselswerepresentinthedermisoftailsthatappearedofred / browncoloratgrossexamination.Inseverecases，thedilatedvascularstructureswerethromboticandaccompaniedbydermalhemorrhagesandfocalcoagulativenecrosisoftheoverlyingepidermis.Thesefindingssuggestthatepidermalacanthosisandhyperkeratosisarethemainandprimaryeventsinthedevelopmentofringtail.Toclarifythecauseofthisdise酶，未来的研究应该集中在可能引起表皮变化的众多因素上。

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《Comparative Medicine》 |2000年第5期|共页
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中图分类畜牧、动物医学、狩猎、蚕、蜂;
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Ringtail in Suckling Munich Wistar Fromter Rats: A Histopathologic Study

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