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Ectopic otoconial formation in the lagena of the pigeon inner ear

机译:鸽子内耳腹腔异位耳锥的形成

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The vertebrate inner ear contains vestibular receptors with dense crystals of calcium carbonate, the otoconia. The production and maintenance of otoconia is a delicate process, the perturbation of which can lead to severe vestibular dysfunction in humans. The details of these processes are not well understood. Here, we report the discovery of a new otoconial mass in the lagena of adult pigeons that was present in more than 70% of birds. Based on histological, tomographic and elemental analyses, we conclude that the structure likely represents an ectopically-formed otoconial assembly. Given its frequent natural occurrence, we suggest that the pigeon lagena is a valuable model system for investigating misregulated otoconial formation.This article has an associated First Person interview with the first author of the paper.
机译:脊椎动物的内耳含有前庭受体,该受体具有致密的碳酸钙晶体,即耳垢。耳菌的产生和维持是一个微妙的过程,其扰动可导致人类严重的前庭功能障碍。这些过程的细节不是很清楚。在这里,我们报告在成年鸽子的巢中发现了一个新的耳锥团,该鸟存在于70%以上的鸟类中。根据组织学,断层扫描和元素分析,我们得出的结论是,该结构可能代表了异位形成的耳锥组装。鉴于其经常发生的自然现象,我们认为拉格纳鸽是一个用于研究耳锥形成失调的有价值的模型系统。本文对第一人进行了第一人称采访。

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