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首页> 外文期刊>Clinical and Experimental Otorhinolaryngology >Antiallergic Effects of Trichostatin A in a Murine Model of Allergic Rhinitis
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Antiallergic Effects of Trichostatin A in a Murine Model of Allergic Rhinitis

机译:Trichostatin A在变应性鼻炎小鼠模型中的抗过敏作用

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Objectives Trichostatin A (TSA), an inhibitor of histone deacetylase, has been shown to play an important role in attenuating asthmatic inflammation. However, the effect of TSA in allergic rhinitis is not known. The aims of this study were to investigate the effect of TSA on allergic nasal inflammation and on the induction of regulatory T cells in a murine model of allergic rhinitis.
机译:目的已证明组蛋白脱乙酰基酶抑制剂曲古他汀A(TSA)在减轻哮喘炎症中起重要作用。然而,TSA在变应性鼻炎中的作用尚不清楚。这项研究的目的是调查在过敏性鼻炎的小鼠模型中TSA对过敏性鼻炎症的影响以及对调节性T细胞的诱导作用。

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