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首页> 外文期刊>Comparative Medicine >Hemodynamic Indices Versus Gastric Tonometric Measurements for Prognosis of Hemorrhagic Shock: A Porcine Model
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Hemodynamic Indices Versus Gastric Tonometric Measurements for Prognosis of Hemorrhagic Shock: A Porcine Model

机译：出血性休克的预后的血流动力学指数与胃压测量法：一种猪模型

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Theaimofthestudyreportedherewastoassesstheprognosticvalueofgastrictonometryanditsimplicationsintheinitialphasesofhemorrhagicshock.Hemorrhagicshockwasinducedbyuseoffemoralarterialbleedingin12hybridswineundergeneralanesthesia.Approximately30%ofthecirculatingbloodvolumewasremoved,untilmeanarterialpressureof45mmHgwasreached.Theshockconditionswereobservedoveralimitedperiod(90min)bycomparingtraditionalhemodynamicparameterswithgastrictonometricmeasurementsandtissueoxygenation.Afterashockperiodof90minwithoutpharmacologictreatment,bloodwascollectedinacid-citratedextrosetreatedbagsandwasreinfusedviatherightfemoralvein.brxmlns="http://pub2web.metastore.ingenta.coms/"/brAttheendoftheexperiment,sevenanimalshadgoodhemodynamicrecoveryonreinfusion(groupA),whereasvaluesinfiveanimalsdeceasedinthesamephase(groupB).Hemodynamicandgastrictonometricresultswerecomparedbetweensurvivorsandnonsurvivors.brxmlns="http://pub2web.metastore.ingenta.coms/"/brIntravascularvolumerestorationandreductionofsystemicvascularresistance(SVR)enabledtheanimalsofgroupAtomaintainstandardventricularkineticsandrecoverintermsofsplanchnicregionalflow.Inaddition,increaseinintramucosalgastricpH(pHi),decreaseinthepH-gap(pHa#8211;Hi),andprogressiverestorationingastricwalltissueoxygenation(PtOsubxmlns="http://pub2web.metastore.ingenta.coms/"2/sub)alsowereobserved.Theseresultssuggestthatusefuldiagnosticandtherapeuticindicationscanbeobtainedbyacquisitionofsimplehemodynamicmeasurementsatthebeginningoftheshockperiod.Onthebasisofresultsofstatisticalanalysis,onlymeanarterialpressureandSVRweregoodindicatorsofshockdevelopment,whereaspHiwasnotasignificantfactorinthisexperimentalmodel.
机译：Theaimofthestudyreportedherewastoassesstheprognosticvalueofgastrictonometryanditsimplicationsintheinitialphasesofhemorrhagicshock.Hemorrhagicshockwasinducedbyuseoffemoralarterialbleedingin12hybridswineundergeneralanesthesia.Approximately30％ofthecirculatingbloodvolumewasremoved，untilmeanarterialpressureof45mmHgwasreached.Theshockconditionswereobservedoveralimitedperiod（90分钟）bycomparingtraditionalhemodynamicparameterswithgastrictonometricmeasurementsandtissueoxygenation.Afterashockperiodof90minwithoutpharmacologictreatment，bloodwascollectedinacid-citratedextrosetreatedbagsandwasreinfusedviatherightfemoralvein。 Attheendoftheexperiment，sevenanimalshadgoodhemodynamicrecoveryonreinfusion（组A），而同一阶段（组B）中五个动物的值下降。血液动力学和血压测量结果在幸存者和非幸存者之间进行了比较。 紧急血管阻力（SVR）可使动物群保持标准的心室动力学并恢复内脏区域内流。此外，增加粘膜胃内pH（pHi），降低pH间隙（pHa＃8211; Hi），并逐步恢复xml / substants（<2。因此，建议在休克期开始时通过简单的血流动力学测量来获得有用的诊断和治疗指征。根据统计分析的结果，只有模型中的动脉压力和SVR显示出良好的迹象，这才表明休克是有力的。

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