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Osteoblastic Osteosarcoma in a Rabbit

机译:兔成骨细胞骨肉瘤

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Anosteosarcomadevelopedinthetarsaljointregioninvolvingthedistaltibiaofadomesticrabbit(Oryctolaguscuniculus).Micrometastaseswerepresentinthelungs.Histologicallythetumorwascomposedofovoidtoshort-spindlecellswithabundantgiantcells,producingirregularislandsofosteoids.Thetumorcellswereimmunopositivewithantiosteocalcinmonoclonalantibody,consistentwiththeirderivationfromosteoblasts.Accordingtoreviewof10publishedcases,productiveosteoblasicosteosarcomaisthemostcommonbonetumorinrabbits,withhalfofallcasesdevelopingintheskullorfacialbones.
机译:Anosteosarcomadevelopedinthetarsaljointregioninvolvingthedistaltibiaofadomesticrabbit(Oryctolaguscuniculus).Micrometastaseswerepresentinthelungs.Histologicallythetumorwascomposedofovoidtoshort-spindlecellswithabundantgiantcells,producingirregularislandsofosteoids.Thetumorcellswereimmunopositivewithantiosteocalcinmonoclonalantibody,consistentwiththeirderivationfromosteoblasts.Accordingtoreviewof10publishedcases,productiveosteoblasicosteosarcomaisthemostcommonbonetumorinrabbits,withhalfofallcasesdevelopingintheskullorfacialbones。

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