Osteoblastic osteosarcoma in a rabbit.

Ishikawa M.; Kondo H.; Onuma M.; Shibuya H.; Sato T.

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Osteoblastic osteosarcoma in a rabbit.

机译：兔中的成骨细胞性骨肉瘤。

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An osteosarcoma developed in the tarsal joint region involving the distal tibia of a domestic rabbit (Oryctolagus cuniculus). Micrometastases were present in the lungs. Histologically the tumor was composed of ovoid to short-spindle cells with abundant giant cells, producing irregular islands of osteoids. The tumor cells were immunopositive with antiosteocalcin monoclonal antibody, consistent with their derivation from osteoblasts. According to review of 10 published cases, productive osteoblasic osteosarcoma is the most common bone tumor in rabbits, with half of all cases developing in the skull or facial bones.

机译：在涉及家兔（ Oryctolagus cuniculus ）胫骨远端的关节区域出现骨肉瘤。肺中存在微转移。从组织学上看，肿瘤由卵圆形到短梭形细胞组成，具有丰富的巨细胞，产生不规则的类骨质岛。肿瘤细胞用抗骨钙蛋白单克隆抗体免疫阳性，这与其从成骨细胞衍生的结果一致。根据对10例已发表病例的回顾，生产性全肋骨肉瘤是兔中最常见的骨肿瘤，所有病例中有一半发生在颅骨或面骨中。

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来源
《Comparative Medicine》 |2012年第2期|共3页
作者
Ishikawa M.; Kondo H.; Onuma M.; Shibuya H.; Sato T.;
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正文语种 eng
中图分类畜牧、动物医学、狩猎、蚕、蜂;
关键词
antibodies; bone diseases; bones; joints (animal); neoplasms; sarcoma; skull; tibia; rabbits; Leporidae; Lagomorpha; mammals; vertebrates; Chordata; animals; eukaryotes; cancers; osteoblasts;

机译：抗体;骨骼疾病;骨骼;关节（动物）;肿瘤;肉瘤;头骨;胫骨;兔子;麻风科;Lagomorpha;哺乳动物;脊椎动物;鱼类;动物;真核生物;癌症;成骨细胞;

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专利

1. Osteoblastic osteosarcoma in a rabbit. [J] . Ishikawa M., Kondo H., Onuma M., Comparative Medicine . 2012,第2期

机译：兔中的成骨细胞性骨肉瘤。
2. Plasma membrane proteomic analysis of human osteosarcoma and osteoblastic cells: revealing NDRG1 as a marker for osteosarcoma [J] . Yingqi Hua, Xiaofang Jia, Mengxiong Sun, Tumor Biology . 2011,第5期

机译：人骨肉瘤和成骨细胞的质膜蛋白质组学分析：揭示NDRG1作为骨肉瘤的标志物
3. Plasma membrane proteomic analysis of human osteosarcoma and osteoblastic cells: revealing NDRG1 as a marker for osteosarcoma. [J] . Hua Y, Jia X, Sun M, Tumour biology : . 2011,第5期

机译：人骨肉瘤和成骨细胞的质膜蛋白质组学分析：揭示NDRG1作为骨肉瘤的标志物。
4. Broadband Microwave Dielectric Property Comparison of Human Fetal Osteoblastic (hFOB) and Osteosarcoma (SaOS-2) Cell Lines [C] . Zeynep Macit, Cemanur Aydinalp, Tuba Yilmaz, European Conference on Antennas and Propagation . 2020

机译：人胎儿成骨细胞（hFOB）和骨肉瘤（SaOS-2）细胞系的宽带微波介电性能比较
5. Evaluating hydroxyapatite microcarriers for the attachment, proliferation, and osteoblastic differentiation of human adult stem cells and a human osteosarcoma cell line. [D] . Loveland, Amy N. 2003

机译：评估羟基磷灰石微载体对人成年干细胞和人骨肉瘤细胞系的附着，增殖和成骨细胞分化的作用。
6. Annexins A2 A6 and Fetuin-A Affect the Process of Mineralization in Vesicles Derived from Human Osteoblastic hFOB 1.19 and Osteosarcoma Saos-2 Cells [O] . Lukasz Bozycki, Joanna Mroczek, Laurence Bessueille, 2021

机译：Annexins A2A6和Fetuin-A影响源自人骨细胞HFOB 1.19和骨肉瘤SAOS-2细胞的囊泡中的矿化过程
7. Establishment of an Osteoblastic Osteosarcoma Cell Line and Effects of Cell Culture Conditions on Secretion of Matrix Metalloproteinases from the Cultured Osteosarcoma Cells. [O] . KAZUHITO MINAMITANI 2000

机译：建立骨细胞骨肉瘤细胞系和细胞培养条件对培养骨肉瘤细胞分泌基质金属蛋白酶的影响。
8. A Virally Induced Osteosarcoma in Rats. A Model for Immunological Studies of Human Osteosarcoma. [R] . Friedlander, G. E., Mitchell, M. S. 1976

机译：大鼠病毒性骨肉瘤。人骨肉瘤免疫学研究模型。

Osteoblastic osteosarcoma in a rabbit.

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