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首页> 外文期刊>Biology Open >vasa is expressed in somatic cells of the embryonic gonad in a sex-specific manner in Drosophila melanogaster
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vasa is expressed in somatic cells of the embryonic gonad in a sex-specific manner in Drosophila melanogaster

机译：vasa在果蝇中以性别特异性方式在胚胎性腺的体细胞中表达

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摘要

Vasa is a DEAD box helicase expressed in the Drosophila germline at all stages of development. vasa homologs are found widely in animals and vasa has become the gene of choice in identifying germ cells. I now show that Drosophila vasa expression is not restricted to the germline but is also expressed in a somatic lineage, the embryonic somatic gonadal precursor cells. This expression is sexually dimorphic, being maintained specifically in males, and is regulated post-transcriptionally. Although somatic Vasa expression is not required for gonad coalescence, these data support the notion that Vasa is not solely a germline factor.
机译：Vasa是果蝇种系在所有发育阶段表达的DEAD盒解旋酶。 vasa同源物在动物中广泛发现，而vasa已成为鉴定生殖细胞的首选基因。我现在显示果蝇vasa的表达不仅限于种系，而且还在体细胞谱系，即胚胎体细胞性腺前体细胞中表达。该表达具有性别双态性，在男性中特别保持，并且在转录后受到调控。尽管性腺合并不需要体细胞Vasa表达，但这些数据支持以下观点：Vasa不仅是种系因子。

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