Lymphoid Organ Alterations Enhanced by SubLethal Doses of Coronaviruses in Experimentally Induced Trypanosoma cruzi Infection in Mice

Verinaud Liana; Camargo Irineu J.B.; Vassallo José; Sakurada Júlia K.; Rangel Humberto A.

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Lymphoid Organ Alterations Enhanced by SubLethal Doses of Coronaviruses in Experimentally Induced Trypanosoma cruzi Infection in Mice

机译：在实验诱导的小鼠克鲁氏锥虫感染中，冠状病毒的次致死剂量增强了淋巴器官的改变。

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Theeffectofsub-lethaldosesofcoronavirusesonthecourseofdiseaseinCBAmiceexperimentallyinfectedwithamildlypathogenicstrainofTrypanosomacruziwasinvestigated.MicewereinoculatedwitheitherT.cruzi,0.1medianlethaldose(LDsubxmlns="http://pub2web.metastore.ingenta.coms/"50/sub)ofcoronavirus(mousehepatitisvirus[MHV-3]orvirusX),orbothpathogens.Levelsofparasitemia,mortality,andtheextentofpathologicalterationsinlymphoidorgansweredetermined.MiceinoculatedwithT.cruzihadmildalterationsintheirlymphoidorgansandsurvivedinfection.Incontrast,miceinoculatedwithbothpathogensdied,andhadsignificantlyhigherlevelsofparasitemiaandprofoundalterationsinlymphoidorgans.TheseresultsindicatethatthepathologicprofileofT.cruziinfectioncanbeprofoundlyalteredbysubclinicalinfectionwithcoronaviruses.

机译：实验研究了用C.Cruzi，0.1medianlethaldose（LD

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《Comparative Medicine》 |1999年第1期|共页
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Verinaud Liana; Camargo Irineu J.B.; Vassallo José; Sakurada Júlia K.; Rangel Humberto A.;
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中图分类畜牧、动物医学、狩猎、蚕、蜂;
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1. Lymphoid organ alterations enhanced by sub-lethal doses of coronaviruses in experimentally induced Trypanosoma cruzi infection in mice. [J] . Verinaud L, Camargo IJB, Vassallo J, Laboratory Animal Science . 1999,第1期

机译：在实验诱导的小鼠克鲁氏锥虫感染中，亚致死剂量的冠状病毒可增强淋巴器官的改变。
2. Acute Trypanosoma cruzi experimental infection induced renal ischemic/reperfusion lesion in mice [J] . Gabriel Melo de Oliveira, Tshaca Mahatma da Silva, Werson Silva Batista, Parasitology Research . 2010,第1期

机译：急性克鲁氏锥虫实验性感染诱发小鼠肾脏缺血/再灌注损伤
3. Acute Trypanosoma cruzi experimental infection induced renal ischemic/reperfusion lesion in mice [J] . Gabriel Melo de Oliveira, Tshaca Mahatma da Silva, Wanderson Silva Batista, Parasitology Research . 2009,第1期

机译：急性克鲁氏锥虫实验性感染诱发小鼠肾脏缺血/再灌注损伤
4. Different peripheral neuroendocrine responses to Trypanosoma cruzi infection in mice lacking adaptive immunity [C] . Eduardo Roggero, Johannes Wildmann, Marcelo O. Passerini, International Society for Neuroimmunomodulation . 2012

机译：不同周围神经内分泌反应对缺乏适应性免疫的小鼠脑蛋白酶瘤Cruzi感染
5. The regulation of infection-induced cardiac autoimmunity and natural dissemination of Trypanosoma cruzi in experimental Chagas heart disease [D] . Hyland, Kenneth V. 2008

机译：实验性南美锥虫性心脏病感染引起的心脏自身免疫性和克鲁氏锥虫自然传播的调节
6. Experimental Trypanosoma cruzi Infection Induces Pain in Mice Dependent on Early Spinal Cord Glial Cells and NFκB Activation and Cytokine Production [O] . Sergio M. Borghi, Victor Fattori, Thacyana T. Carvalho, 2020

机译：实验性锥虫瘤Cruzi感染诱导小鼠疼痛依赖于早期脊髓胶质细胞和NFκB活化和细胞因子生产
7. TcVac1 vaccine delivery by intradermal electroporation enhances vaccine induced immune protection against Trypanosoma cruzi infection in mice [O] . Wael Hegazy-Hassan, José Antonio Zepeda-Escobar, Laucel Ochoa-García, 2019

机译：通过皮内电穿孔的TCVAC1疫苗递送增强了对小鼠的促蛋白酶瘤Cruzi感染的疫苗诱导的免疫保护

Lymphoid Organ Alterations Enhanced by SubLethal Doses of Coronaviruses in Experimentally Induced Trypanosoma cruzi Infection in Mice

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