Chitin, Chitosan, and Glycated Chitosan Regulate Immune Responses: The Novel Adjuvants for Cancer Vaccine

Xiaosong Li; Min Min; Nan Du; Ying Gu; Tomas Hode; Mark Naylor; Dianjun Chen; Robert E. Nordquist; Wei R. Chen

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Chitin, Chitosan, and Glycated Chitosan Regulate Immune Responses: The Novel Adjuvants for Cancer Vaccine

机译：甲壳素，壳聚糖和糖化壳聚糖调节免疫反应：癌症疫苗的新型佐剂。

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With the development of cancer immunotherapy, cancer vaccine has become a novel modality for cancer treatment, and the important role of adjuvant has been realized recently. Chitin, chitosan, and their derivatives have shown their advantages as adjuvants for cancer vaccine. In this paper, the adjuvant properties of chitin and chitosan were discussed, and some detailed information about glycated chitosan and chitosan nanoparticles was also presented to illustrate the trend for future development.

机译：随着癌症免疫疗法的发展，癌症疫苗已经成为一种新型的癌症治疗手段，并且佐剂的重要作用近来已经得到认识。几丁质，壳聚糖及其衍生物已显示出作为癌症疫苗佐剂的优势。本文讨论了几丁质和壳聚糖的佐剂性质，并提供了一些有关糖化壳聚糖和壳聚糖纳米颗粒的详细信息，以说明未来的发展趋势。

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《Clinical & developmental immunology.》 |2013年第2期|共8页
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Xiaosong Li; Min Min; Nan Du; Ying Gu; Tomas Hode; Mark Naylor; Dianjun Chen; Robert E. Nordquist; Wei R. Chen;
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中图分类免疫性疾病;
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1. Chitin, Chitosan, and Glycated Chitosan Regulate Immune Responses: The Novel Adjuvants for Cancer Vaccine [J] . Xiaosong Li, Min Min, Nan Du, Clinical & developmental immunology. . 2013,第Pta1期

机译：甲壳素，壳聚糖和糖化壳聚糖调节免疫反应：癌症疫苗的新型佐剂。
2. Th immune response induced by H pylori vaccine with chitosan as adjuvant and its relation to immune protection [J] . Yong Xie, Nan-Jin Zhou, Yan-Feng Gong, World Journal of Gastroenterology . 2007,第10期

机译：壳聚糖佐剂对幽门螺杆菌疫苗的免疫应答及其与免疫保护的关系
3. Improved immune responses in mice using the novel chitosan adjuvant ViscoGel, with a Haemophilus influenzae type b glycoconjugate vaccine. [J] . Neimert-Andersson T., Hallgren A. C., Andersson M., Vaccine . 2011,第48期

机译：使用新型壳聚糖佐剂ViscoGel和流感嗜血杆菌b型糖缀合物疫苗可改善小鼠的免疫反应。
4. Activity of glycated chitosan and other adjuvants to PDT vaccines [C] . Mladen Korbelik, Judit Banath, Evaldas Ciplys, Biophotonics and immune responses X . 2015

机译：糖化壳聚糖和其他佐剂对PDT疫苗的活性
5. Chitosan-based membranes regulate human mesenchymal stem cell response in guided bone regeneration. [D] . Hunter, Kimberly T. 2013

机译：基于壳聚糖的膜在引导的骨再生中调节人间充质干细胞反应。
6. Chitin Chitosan and Glycated Chitosan Regulate Immune Responses: The Novel Adjuvants for Cancer Vaccine [O] . Xiaosong Li, Min Min, Nan Du, 2013

机译：甲壳素壳聚糖和糖化壳聚糖调节免疫反应：癌症疫苗的新型佐剂。
7. Modulation of Immune Response to Group C Meningococcal Conjugate Vaccine Given Intranasally to Mice Together with the LTK63 Mucosal Adjuvant and the Trimethyl Chitosan Delivery System [O] . Barbara C. Baudner, Maurizio Morandi, Marzia M. Giuliani, 2004

机译：与LTK63粘膜佐剂和三甲基壳聚糖递送系统一起对小鼠进行C组脑膜炎球菌缀合物疫苗的免疫反应的调节

Chitin, Chitosan, and Glycated Chitosan Regulate Immune Responses: The Novel Adjuvants for Cancer Vaccine

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