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Expression of a Novel Protein by Regenerating Hepatocytes and Peripheral Blood Lymphocytes

机译:通过再生肝细胞和外周血淋巴细胞表达一种新型蛋白质

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Regeneration and tolerance factor (RTF) is a protein with immunosuppressive activity and is normally present in the thymus and placenta. RTF was measured in the livers of patients with regenerating nodules due to alcoholic cirrhosis and hepatitis C. RTF was expressed in the regenerating nodules of 26 patients with alcoholic cirrhosis. All patients with chronic hepatitis C without cirrhosis failed to express RTF. Flow cytometry revealed upregulation of RTF on the lymphocytes from alcoholic cirrhosis and downregulation in hepatitis C disease.
机译:再生和耐受因子(RTF)是一种具有免疫抑制活性的蛋白质,通常存在于胸腺和胎盘中。在酒精性肝硬化和丙型肝炎引起的结节性再生患者的肝脏中测量RTF。26例酒精性肝硬化的再生性结节中表达RTF。所有无肝硬化的慢性丙型肝炎患者均未表达RTF。流式细胞仪显示酒精性肝硬化淋巴细胞的RTF上调,丙型肝炎疾病下调。

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