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首页> 外文期刊>Clinical and diagnostic laboratory immunology >Humoral antibody to Mobiluncus curtisii, a potential serological marker for bacterial vaginosis.
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Humoral antibody to Mobiluncus curtisii, a potential serological marker for bacterial vaginosis.

机译：Mocuruncus curtisii的体液抗体，一种细菌性阴道病的潜在血清学标志物。

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While bacterial vaginosis (BV) is a polymicrobial syndrome, Mobiluncus spp. are the organisms most highly associated with this condition. It is possible that serum antibody to Mobiluncus spp. could be used as a serological marker for BV. Using immunofluorescence techniques, we studied the prevalence of antibody to M. curtisii among three cohorts-pregnant women, pediatric patients, and sexually inexperienced women. The prevalence of antibody in each of these three groups was 75, 6, and 0%, respectively. Of the three pediatric patients with antibody to Mobiluncus curtisii, two were neonates, and the only class of antibody detected was immunoglobulin G. Among the cohort of pregnant women, the presence of antibody could not be correlated with a clinical history of BV. Serum antibody to M. curtisii could be a useful serological marker for BV. The lack of correlation of antibody positivity to historical information regarding BV suggests that unrecognized or undiagnosed episodes of BV may be common.
机译：细菌性阴道病（BV）是一种多微生物综合症，而Mobiluncus spp。是与这种情况高度相关的生物。可能有针对Mobiluncus spp的血清抗体。可用作BV的血清学标志物。使用免疫荧光技术，我们研究了三名队列妊娠孕妇，儿科患者和性经验不足的妇女中抗麻风杆菌的抗体的患病率。这三组抗体的患病率分别为75％，6％和0％。在三名患马齿unc的抗体的儿科患者中，两名是新生儿，并且检测到的唯一一类抗体是免疫球蛋白G。在孕妇队列中，抗体的存在与BV的临床病史无关。抗curtisii的血清抗体可能是BV有用的血清学标志物。抗体阳性与有关BV的历史信息之间缺乏相关性，提示无法识别或未诊断的BV发作可能很常见。

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