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首页> 外文期刊>Acta medica Okayama >Formulae Based on Biomathematics to Estimate the Standard Value of Fetal Growth of Japanese
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Formulae Based on Biomathematics to Estimate the Standard Value of Fetal Growth of Japanese

机译：基于生物数学的公式来估算日本人胎儿生长的标准值

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We devised biomathematics-based formulae to estimate the standard values of fetal growth of Japanese after 22 weeks' gestation. The growth rates of bi-parietal diameter (BPD), abdominal circumference (AC), femur length (FL), and estimated fetal body weight (EFBW) at the time of gestation were assumed to be proportional to the product of the value at the time and the rest value of an unknown maximum value, respectively. The EFBW was also assumed to follow a multiple logistic function of BPD, AC and FL to fit the standard values of Japanese fetuses published by the Japan Society of Ultrasonics in Medicine. The Mann-Whitney test was used for statistical analysis. The values as a function of gestational day, t, were as follows: BPD(t)=99.6/(1+exp (2.725?0.01837＊t)) (mm); AC(t)=39.7/(1+exp (2.454?0.01379＊t)) (cm); FL(t)=79.6/(1+exp (2.851?0.01710＊t)) (mm); EFBW(t)=8045.1/(1+exp (6.028?0.06582＊BPD(t)?0.1469＊AC(t)+ 0.07377＊FL(t))) (g). EFBW as a function of BPD, AC and FL was as follows: EFBW=8045.1/(1+exp (4.747+ 0.02584＊BPD+0.1010＊AC?0.1416＊FL)) (g). When the BPD, AC and FL were at ?2 standard deviation (SD), ?1SD, mean and + 2SD, the EFBW values calculated by the formula were statistically closer to the standard values than conventional formulas with p-values of 4.871×10?7, 4.228×10?7, 9.777×10?7 and 0.028, respectively. The formulae based on biomathematics might be useful to estimate the fetal growth standard values.
机译：我们设计了基于生物数学的公式，以估算妊娠22周后日本人胎儿生长的标准值。假定妊娠时双顶径（BPD），腹围（AC），股骨长度（FL）和估计的胎儿体重（EFBW）的生长速率与该值的乘积成比例。时间和未知最大值的剩余值。还假定EFBW遵循BPD，AC和FL的多重逻辑函数，以符合日本超声医学会发布的日本胎儿的标准值。使用Mann-Whitney检验进行统计分析。该值作为胎龄t的函数如下：BPD（t）= 99.6 /（1 + exp（2.725？0.01837 ＊ t））（mm）; AC（t）= 39.7 /（1 + exp（2.454？0.01379 ＊ t））（cm）; FL（t）= 79.6 /（1 + exp（2.851？0.01710 ＊ t））（mm）; EFBW（t）= 8045.1 /（1 + exp（6.028？0.06582 * BPD（t）？0.1469 * AC（t）+ 0.07377 * FL（t）））（g）。 EFBW作为BPD，AC和FL的函数如下：EFBW = 8045.1 /（1 + exp（4.747+ 0.02584 ＊ BPD + 0.1010 ＊ AC？0.1416 ＊ FL））（g）。当BPD，AC和FL分别为±2标准偏差（SD），±1SD，平均值和+ 2SD时，该公式计算出的EFBW值在统计上比p值为4.871×10的常规公式更接近标准值。分别为φ7、4.228×10φ7、9.777×10φ7和0.028。基于生物数学的公式可能有助于估计胎儿生长标准值。

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