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The effect of intrahypothalamic serotonin reinforcement on directional preference in rats

机译:下丘脑5-羟色胺增强对大鼠定向偏向的影响

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Reinforcing properties of serotonin administration to the lateral hypothalamus were tested on the experimental model of the T-maze learning in 19 rats. The results did not definitely prove either positive or negative reinforcement produced by the central serotonergic stimulation, although the rats modified their behavior in the maze in the response to intrahypothalamic serotonin. It seems that the central serotonergic neurons do not play a decisive role in the mediation of the reinforcing phenomena but they may interact with the activity of some other reward neurons.
机译:在19只大鼠的T-迷宫学习实验模型上测试了5-羟色胺向下丘脑外侧给药的增强特性。尽管大鼠根据对下丘脑内5-羟色胺的反应改变了其在迷宫中的行为,但结果并未明确证明由中枢5-羟色胺能刺激产生正或负的增强作用。似乎中央的5-羟色胺能神经元在增强现象的介导中没有决定性作用,但它们可能与某些其他奖励神经元的活动相互作用。

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