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Trend and manifestations of falciparum malaria in a tertiary care hospital of India

机译:印度三级医院恶性疟疾的趋势和表现

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Background: The recent focus is on the increase in the burden of falciparum cases with a varied spectrum of presentation and outcome, especially in developing countries like India. This study was undertaken to analyze the trend and manifestations of falciparum malaria in a tertiary care hospital. Materials and Methods: This descriptive study was carried out at the Gauhati Government Medical College and Hospital from June 2006 to May 2007. The data were collected on demographic and time characteristics, clinical and laboratory findings, the outcome of disease and expressed in proportion or percentages. Results: Out of the 100 cases, around 2nd/3rd (63%) of cases were in the age group of 15–30 years and the mean age was found to be 29.51 years. About 66% of them were males. Clinical presentations included pain abdomen (42, 42%), nausea and vomiting (35, 35%), jaundice (34, 34%), oliguria (24, 24%), altered sensorium (24, 24%), breathing difficulty (10, 10%), and seizures (5, 5%). Number of cases and mortality were more with a peak in the month of May and September. Manifestations of severe falciparum malaria included hepatopathy (38%), renal failure (28%), shock (9%), acute respiratory distress syndrome (7%), hypoglycemia (3%), and severe anemia (1%). Eighty-two cases (82%) recovered and 18 cases (18%) expired. Conclusion: Falciparum malaria is more among younger adult age group and males. Complications and mortality are also more due to falciparum malaria.
机译:背景:最近的关注点是恶性肿瘤病例的负担增加,表现形式和结果各异,尤其是在印度等发展中国家。这项研究旨在分析三级医院恶性疟疾的趋势和表现。材料和方法:该描述性研究于2006年6月至2007年5月在高哈蒂政府医学院和医院进行。收集了有关人口统计学和时间特征,临床和实验室检查结果,疾病结局的数据,并按比例或百分比表示。结果:在这100例病例中,大约2 / 3 rd 例(63%)处于15-30岁年龄组,并且发现了平均年龄是29.51年。其中约66%是男性。临床表现包括腹部疼痛(42%,42%),恶心和呕吐(35%,35%),黄疸(34%,34%),少尿(24%,24%),感觉觉改变(24%,24%),呼吸困难( 10%,10%)和癫痫发作(5%,5%)。病例数和死亡率更多,5月和9月达到峰值。严重恶性疟疾的表现包括肝病(38%),肾衰竭(28%),休克(9%),急性呼吸窘迫综合征(7%),低血糖(3%)和严重贫血(1%)。康复了82例(82%),18例(18%)过期。结论:恶性疟疾在年轻人和男性中更为常见。并发症和死亡率也更多是由于恶性疟疾。

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