• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>International Journal of Prevention and Treatment >Trend, Manifestations and Outcome of Falciparum Malaria Infection in Wad-Medani Teaching Hospital in the Central Region of Sudan
【24h】

Trend, Manifestations and Outcome of Falciparum Malaria Infection in Wad-Medani Teaching Hospital in the Central Region of Sudan

机译：苏丹中部瓦德迈丹尼教学医院恶性疟疾感染的趋势，表现和结果

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background: Malaria is one of the most common diseases affecting humans worldwide. It remains a major global public health and a major cause of morbidity and mortality in tropical and subtropical countries. Plasmodium falciparum malaria is the most dangerous and fatal form of illness, and it is the most common species prevalent in Sudan throughout the year. Gastrointestinal manifestations are common in malaria endemic areas. Malaria occasionally presents with both typical and atypical symptoms and signs, and there is an increase burden on health services in hospitals, due to large spectrum of falciparum malaria presentation and outcome, especially in Gezira area in Sudan. Objectives: To assess the trend, manifestations and outcome of falciparum malaria infection in patients admitted to medical wards. Methods: This is descriptive, prospective, cross sectional hospital-based study, conducted in Wad Medani Teaching Hospital in the central region of Sudan in the period of December 2014 to May 2015. Results: A total of 160 patients were admitted with severe malaria during period from December 2014 to May 2015. The age of study populations ranged from 15 - 80 years, with mean age (43.11), with the most affected patients in age group 15 - 45 years. Males were 86 (53.8%) and females 74 (46.3%). The main manifestations and complication of severe falciparum malaria in this study were: hyperparasitemia which present in 90 (56.3%), then Hypotension or circulatory collapse was observed in 52 (32.5%), hyperpyrexia was seen in 35 (21.9%), prostration and weakness seen in 33 (20.6%), cerebral malaria with loss of consciousness seen in 19 (11.9%), acute kidney injury (AKI) was seen in 18 (11.3%), hypoglycemia was seen in 18 (11.3%), repeated convulsions ≥ 3 frequency occurred in 14(8.8%), severe anemia was seen in 10(6.3%), abnormal bleeding occurred in 10(6.3%), and hyperbilirubinemia also in 10 (6.3%). Pulmonary oedema was found in 2 cases (1.3%), and disseminate intravascular coagulation (DIC) in 2 (1.3%), blackwater fever in one case (0.6%). Other complications like acute respiratory distress syndrome (ARDS) and acidosis were not reported in this study. Patients who received quinine hydrochloride salt via intravenous infusion were 153 (95.6%), and who received artemether injection were 7(4.4%). Some patients received supportive management according to their presentation. The main duration of hospital stay was 3-5 days in 87 (54.4%). The outcome was as follows: 154 (96.3%) improved and were discharged in a good condition, and Six patients (3.8%) died. Conclusion: Falciparum malaria is more among younger adult age group and male. The main manifestations and complications of severe falciparum malaria infection were hyperparasitemia, hypotension, hyperpyrexia, prostration and weakness, cerebral malaria, AKI then hypoglycemia and repeated convulsions, severe anemia. Most of the patients treated with quinine with very good response, and the mortality rate was 3.8%.
机译：背景：疟疾是影响全世界人类的最常见疾病之一。它仍然是全球主要的公共卫生，也是热带和亚热带国家发病率和死亡率的主要原因。恶性疟原虫疟疾是最危险和致命的疾病，也是苏丹全年最普遍的物种。胃肠道疾病在疟疾流行地区很常见。疟疾偶尔会同时表现出典型和非典型的症状和体征，由于恶性疟疾呈报和后果的范围很大，尤其是在苏丹的吉济拉地区，医院的医疗服务负担增加。目的：评估就诊于病房的恶性疟疾感染的趋势，表现和结果。方法：这是一项描述性，前瞻性，横断面医院研究，于2014年12月至2015年5月在苏丹中部的瓦德梅达尼教学医院进行。结果：在此期间，共收治了160名严重疟疾患者研究人群的年龄范围为2014年12月至2015年5月。研究人群的年龄范围为15-80岁，平均年龄为（43.11），受影响最大的患者是15-45岁。男性为86（53.8％），女性为74（46.3％）。严重恶性疟疾的主要表现和并发症为：高寄生虫血症占90（56.3％），然后低血压或循环衰竭发生在52（32.5％），高热血症发生在35（21.9％），虚脱和虚弱33例（20.6％），脑疟疾伴意识丧失19例（11.9％），急性肾损伤（AKI）18例（11.3％），低血糖18例（11.3％），反复惊厥≥3频率发生在14（8.8％），严重贫血发生在10（6.3％），异常出血发生在10（6.3％），高胆红素血症也发生在10（6.3％）。肺水肿2例（1.3％），弥散性血管内凝血（DIC）2例（1.3％），黑水发烧1例（0.6％）。该研究未报告其他并发症，如急性呼吸窘迫综合征（ARDS）和酸中毒。静脉滴注盐酸奎宁盐的患者为153（95.6％），注射蒿甲醚的患者为7（4.4％）。一些患者根据他们的表现接受了支持治疗。 87名患者的主要住院时间为3-5天（54.4％）。结果如下：154例（96.3％）病情好转，出院情况良好，有6例患者（3.8％）死亡。结论：恶性疟疾在年轻人和男性中更多。严重恶性疟疾感染的主要表现和并发症为高寄生虫血症，低血压，高热，虚弱无力，脑部疟疾，AKI，低血糖和反复抽搐，严重贫血。奎宁治疗的大多数患者反应良好，死亡率为3.8％。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号