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首页> 外文期刊>Advances in Aging Research >Can Ophthalmoscope Predict Silent Coronary Artery Disease in Patients with Type 2 Diabetes Mellitus?
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Can Ophthalmoscope Predict Silent Coronary Artery Disease in Patients with Type 2 Diabetes Mellitus?

机译：检眼镜可以预测2型糖尿病患者的沉默冠状动脉疾病吗？

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Background & Aim: Diabetic retinopathy (DR) and Coronary Artery Disease (CAD) share similar pathophysiological background of vascular damage. So we aimed to study the relationship between DR and silent CAD in patients with type 2 diabetes mellitus (T2DM). Subject & Methods: A cross sectional study was performed on 40 patients with T2DM from diabetic outpatient clinic in Ain Shams University Hospitals, Cairo, Egypt from June 2012 to December 2012. All patients were subjected to data collection, laboratory analysis and imaging studies. Patients with known CAD, abnormal resting or stress ECG, abnormal ejection fraction or segmental wall motion abnormalities, smoking history, hypertension, or abnormal lipid profile were excluded. Results: Mean age is 62.35 ± 1.38 years, 75% (n = 30) were females, 75% (n = 30) had DR, and 77.50% (n = 31) had positive Tc99 scan. There is a significant positive association between Tc99 scan and DR (p value = 0.029) as 86.7% of patients with DR had positive Tc99 scan. Resting and stress perfusion TC99 scan were significantly worse (91.77% vs 100%; 86.48% vs 96.27%, p value = 0.008, 0.005 respectively) and microalbuminuria were significantly higher (207 ± 29.65 vs 36 ± 10.66 mg/dl, p value =99 scan is recommended in patients with DR even if asymptomatic. More multi-centric prospective studies are needed to elucidate the effect of the degree of DR on CAD risk.
机译：背景与目的：糖尿病性视网膜病变（DR）和冠状动脉疾病（CAD）具有相似的血管损伤病理生理背景。因此，我们旨在研究2型糖尿病（T2DM）患者的DR与沉默CAD之间的关系。对象与方法：2012年6月至2012年12月在埃及开罗的艾因沙姆斯大学医院的糖尿病门诊对40例T2DM患者进行了横断面研究。所有患者均接受了数据收集，实验室分析和影像学研究。排除具有已知CAD，异常静息或心电图异常，射血分数异常或节段性壁运动异常，吸烟史，高血压或血脂异常的患者。结果：平均年龄为62.35±1.38岁，女性为75％（n = 30），DR为75％（n = 30），Tc99扫描阳性为77.50％（n = 31）。 Tc99扫描与DR之间存在显着的正相关（p值= 0.029），因为86.7％的DR患者Tc99扫描呈阳性。静息和压力灌注TC99扫描显着更差（91.77％，vs 100％; 86.48％，vs 96.27％，p值分别为0.008、0.005）和微量白蛋白尿明显更高（207±29.65 vs 36±即使是无症状的DR患者，也推荐10.66 mg / dl，p值= 99扫描，甚至需要更多的多中心前瞻性研究来阐明DR程度对CAD风险的影响。

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