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首页> 外文期刊>Acute and critical care. >Status Epilepticus and Beyond: A Clinical Review of Status Epilepticus and an Update on Current Management Strategies in Super-refractory Status Epilepticus
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Status Epilepticus and Beyond: A Clinical Review of Status Epilepticus and an Update on Current Management Strategies in Super-refractory Status Epilepticus

机译：癫痫持续状态及其超越：癫痫持续状态的临床回顾及超难治性癫痫持续状态的当前管理策略更新

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摘要

Status epilepticus and refractory status epilepticus represent some of the most complex conditions encountered in the neurological intensive care unit. Challenges in management are common as treatment options become limited and prolonged hospital courses are accompanied by complications and worsening patient outcomes. Antiepileptic drug treatments have become increasingly complex. Rational polytherapy should consider the pharmacodynamics and kinetics of medications. When seizures cannot be controlled with medical therapy, alternative treatments, including early surgical evaluation can be considered; however, evidence is limited. This review provides a brief overview of status epilepticus, and a recent update on the management of refractory status epilepticus based on evidence from the literature, evidence-based guidelines, and experiences at our institution.
机译：癫痫持续状态和难治性癫痫持续状态代表了神经科重症监护病房遇到的一些最复杂的疾病。由于治疗选择有限，医院病程延长，伴随并发症和患者转归恶化，管理方面的挑战很普遍。抗癫痫药治疗已经变得越来越复杂。合理的综合疗法应考虑药物的药效学和动力学。当癫痫发作无法通过药物治疗来控制时，可以考虑其他替代治疗方法，包括早期手术评估。但是，证据有限。这篇综述提供了对癫痫持续状态的简要概述，并根据文献资料，循证指南和我们机构的经验对难治性癫痫持续状态的管理进行了最新更新。

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