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首页> 外文期刊>Acute Medicine & Surgery >Refractory status epilepticus, circulatory collapse after cardiac arrest, and acute respiratory distress syndrome caused by severe isolated fluvoxamine poisoning: a case report
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Refractory status epilepticus, circulatory collapse after cardiac arrest, and acute respiratory distress syndrome caused by severe isolated fluvoxamine poisoning: a case report

机译：严重隔离氟伏沙明中毒引起的难治性癫痫持续状态，心脏骤停后循环衰竭和急性呼吸窘迫综合征：一例报告

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Case A 30‐year‐old female ingested 21.75?g fluvoxamine in a suicide attempt. She presented with grand mal seizures and vomiting on admission to our E mergency C enter, with a fluvoxamine serum concentration of 4.58?μg/ mL . The patient was diagnosed with status epilepticus, which could not be fully suppressed with the maximum dosage of benzodiazepines. The patient also developed circulatory collapse after resuscitation for sudden cardiac arrest and acute respiratory distress syndrome, believed to be secondary to aspiration. Outcome With venoarterial extracorporeal membrane oxygenation, a massive infusion of propofol successfully suppressed status epilepticus, and both the circulatory collapse and acute respiratory distress syndrome gradually improved; venoarterial extracorporeal membrane oxygenation and propofol treatments were then terminated, and the patient was discharged without further disabilities. Conclusion Compared to all other reported clinical cases of fluvoxamine poisoning, the patient in this study ingested the highest dose and developed the most severe symptoms, but was successfully treated without any disabilities.
机译：案例一名30岁的女性自杀未遂，摄入了21.75？g氟伏沙明。在进入我们的E应急C入口时，她出现了巨大的癫痫发作和呕吐，氟伏沙明血清浓度为4.58？μg/ mL。该患者被诊断为癫痫持续状态，使用最大剂量的苯二氮卓类药物不能完全抑制癫痫持续状态。复苏后，患者还会因突然的心脏骤停和急性呼吸窘迫综合征而发展为循环衰竭，据信这是继发于吸入的。结果通过静脉动脉体外膜氧合，大量输注丙泊酚成功抑制了癫痫持续状态，循环衰竭和急性呼吸窘迫综合征逐渐得到改善。然后终止静脉动脉体外膜氧合和丙泊酚治疗，患者出院而无进一步的残疾。结论与所有其他已报告的氟伏沙明中毒的临床病例相比，本研究中的患者摄入最高剂量并出现最严重的症状，但已成功治愈，没有任何残疾。

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