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首页> 外文期刊>Acute Medicine & Surgery >Quick sepsis‐related organ failure assessment score as a possible predictor for in‐hospital adverse events in infective endocarditis
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Quick sepsis‐related organ failure assessment score as a possible predictor for in‐hospital adverse events in infective endocarditis

机译：快速败血症相关的器官衰竭评估评分可能是感染性心内膜炎医院内不良事件的预测指标

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Aim Infective endocarditis ( IE ) can be life‐threatening because of various associated adverse events. The quick Sepsis‐related Organ Failure Assessment ( qSOFA ) score is a straightforward useful method for predicting in‐hospital mortality in patients with suspected infections. However, few data exist regarding the clinical impact of the qSOFA score on predicting adverse events in IE during hospitalization. We studied the usefulness of qSOFA score for predicting in‐hospital adverse events in patients with IE. Methods We retrospectively analyzed 104 consecutive patients diagnosed with IE on the basis of modified Duke criteria. We defined in‐hospital adverse events as occurrence of any of the following events during hospitalization: death, embolism, hemorrhage, or abscess formation. The high qSOFA group was defined as those with a qSOFA score ≥2. We used Cox regression analysis to estimate the hazard ratio for high qSOFA score on in‐hospital adverse events adjusted for age, sex, andStaphylococcus aureus infection. Results We analyzed 83 patients (57 men, mean age 61?±?18?years) from the total cohort of 104 patients enrolled. Among these, 12 (14.5%) had high qSOFA scores. The high qSOFA group had higher in‐hospital mortality compared to the low qSOFA group (50.0% vs. 4.2%,P ?
机译：目的由于各种相关的不良事件，传染性心内膜炎（IE）可能危及生命。快速的脓毒症相关器官衰竭评估（qSOFA）评分是预测可疑感染患者住院死亡率的直接有用的方法。但是，关于qSOFA评分对预测住院期间IE中不良事件的临床影响的数据很少。我们研究了qSOFA评分在预测IE患者住院期间不良事件中的作用。方法我们根据改良的Duke标准回顾性分析了104例连续诊断为IE的患者。我们将院内不良事件定义为住院期间发生的以下任何事件：死亡，栓塞，出血或脓肿形成。高qSOFA组定义为qSOFA得分≥2的组。我们使用Cox回归分析来估计针对qSOFA得分较高的风险比，该风险针对因年龄，性别和金黄色葡萄球菌感染而调整的院内不良事件。结果我们分析了104例患者中的83例患者（57例男性，平均年龄61±18岁）。其中，有12个（14.5％）的qSOFA得分较高。与低qSOFA组相比，高qSOFA组的院内死亡率更高（50.0％对4.2％，P <0.01）。在Cox比例风险模型中，高qSOFA与院内不良事件显着相关（调整后的风险比为2.29;置信区间为1.02-5.12; P = 0.044）。结论这些结果表明，高qSOFA评分与IE患者的院内不良事件显着相关，尽管需要进一步的前瞻性研究来证实我们的结果。我们发现，高qSOFA评分与IE患者的院内不良结局显着相关。这是第一项表明qSOFA评分也可能是IE患者住院期间危险分层的有用工具。

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