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首页> 外文期刊>Advances in Life Science and Technology >An Observational Descriptive Cross-Sectional Study of 200 Iraqi Adult Patients with Ankylosing Spondylitis: Analysis of Ocular Manifestations
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An Observational Descriptive Cross-Sectional Study of 200 Iraqi Adult Patients with Ankylosing Spondylitis: Analysis of Ocular Manifestations

机译：观察性描述性横断面研究200例伊拉克成人强直性脊柱炎患者：眼部表现分析

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Objective: To analyze the ocular findings in adult patients with ankylosing spondylitis. Patients and methods: A cross sectional study was conducted on (200) ankylosing spondylitis (AS) patients diagnosed according to the modified New York criteria for ankylosing spondylitis. Demographic and clinical data were collected and all patients were examined by same ophthalmologist for ocular findings. Results: The mean age of patients was (35.2 ± 8.6) years with male to female ratio (13.3:1), and mean disease duration was (10.9 ± 6.7) years. Family history of AS was positive in (26%) of patients. HLA-B27 was obtained in (69.5%) of the total number of the patients. Among those patients in whom HLA-B27 test was obtained, (43.2%) had positive HLA-B27. Enthesitis was found in (48%) of patients, and (63.5%) had peripheral arthritis. Ocular manifestations were found in (21.5%) of the patients in the form of anterior uveitis (14.5%), conjunctivitis (3%), ocular dryness (2%), and cataract (2%). Ocular manifestations had significant association with enthesitis, peripheral arthritis, HLA-B27 positivity and positive family history of AS (p 0.05). Conclusions: Prevalence of ocular manifestations in adult Iraqi patients with AS was (21.5%). The commonest form was anterior uveitis. Other forms included conjunctivitis, ocular dryness, and cataract. Ocular manifestations had significant association only with enthesitis, peripheral arthritis, HLA-B27 positivity and positive family history of AS. This may suggest that early screening for ocular features in AS is important for early diagnosis and treatment.
机译：目的：分析成人强直性脊柱炎患者的眼部表现。患者和方法：根据改良的纽约州强直性脊柱炎标准，对200例确诊为强直性脊柱炎（AS）的患者进行了横断面研究。收集人口统计学和临床​​数据，并由同一位眼科医生检查所有患者的眼部发现。结果：患者的平均年龄为（35.2±8.6）岁，男女比例（13.3：1），平均病程为（10.9±6.7）年。 AS的家族史在患者中为阳性（26％）。在患者总数中（69.5％）获得了HLA-B27。在获得HLA-B27检测的患者中，（43.2％）的HLA-B27阳性。在（48％）患者中发现了脑炎，并且（63.5％）患者患有周围关节炎。 （21.5％）的患者以前葡萄膜炎（14.5％），结膜炎（3％），眼干燥（2％）和白内障（2％）的形式出现眼部表现。眼部表现与皮炎，周围关节炎，HLA-B27阳性和AS阳性家族史密切相关（p 0.05）。结论：伊拉克成人AS患者的眼部表现患病率为（21.5％）。最常见的形式是前葡萄膜炎。其他形式包括结膜炎，眼干燥和白内障。眼部表现仅与皮炎，外周关节炎，HLA-B27阳性和AS阳性家族史密切相关。这可能表明早期筛查AS的眼部特征对于早期诊断和治疗很重要。

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