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首页> 外文期刊>African Journal of Biotechnology >Effect of ethanol seed extract of Buccholzia coriacea (wonderful kola) on the lipid profile of albino rats
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Effect of ethanol seed extract of Buccholzia coriacea (wonderful kola) on the lipid profile of albino rats

机译：桔梗乙醇种子提取物对白化病大鼠血脂的影响

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This study investigates the effect of ethanol extract of?Buccholzia coriacea?seeds on the serum lipid profile of albino rats within a period of two weeks of treatments. Twelve (12) Wistar albino rats weighing between 85 to 130?g purchased and randomly divided into three groups?were used for this study. The control group received normal saline while the two other groups received graded doses of 100 and 200?mg/kg body weight of the extract, respectively. Measurement of the serum lipid profile in rats administered with extract indicated a significant decrease (p0.05) between?the?total cholesterol concentration and triacylglycerol concentrations of rats administered with the same extract compared to the control. This study suggests that ethanol extract of?B. coriacea?seeds have active ingredients that are capable of improving the lipid profile and thus, might be useful in the management of cardiovascular diseases caused by hyperlipidemia.
机译：这项研究调查了在两周的治疗时间内，B子花椰菜种子的乙醇提取物对白化病大鼠血清脂质谱的影响。购买了十二（12）只体重在85至130g之间的Wistar白化病大鼠，随机分为三组。对照组接受生理盐水，而另外两组则分别接受100和200？mg / kg体重的分级剂量。测量给予提取物的大鼠的血脂谱表明与给予相同提取物的大鼠的总胆固醇浓度和三酰甘油浓度之间显着降低（p0.05）。这项研究表明乙醇提取了βB。 ia子种子具有能够改善脂质分布的活性成分，因此可能在高脂血症引起的心血管疾病的治疗中有用。

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