• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>African Journal of Biotechnology >Treatment of Helicobacter pylori infections: Mitigating factors and prospective natural remedies
【24h】

Treatment of Helicobacter pylori infections: Mitigating factors and prospective natural remedies

机译：幽门螺杆菌感染的治疗：缓解因素和预期的自然疗法

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Helicobacter pylori?is a Gram-negative, microaerophilic spiral or motile rod that infects about half the world’s population with a very high prevalence in the developing world. It is an important aetiological factor in the development of gastritis, peptic ulcer disease, gastric atrophy and B cell mucosa associated lymphoid tissue (MALT) lymphoma.?H. pylori?infection is responsible for a significant cause of morbidity and mortality imposing a major burden on health care systems world wide. The high prevalence of infection in the developing countries has been attributed to poor socioeconomic status and sanitation as well as an increased trend of antibiotic resistance. Antimicrobial chemotherapy (two antibiotics and a proton pump inhibitor) employed for the treatment of?H. pylori?infections has emerged as the most important means to resolve these?infections. However, antimicrobial therapy is fraught with a number of inherent limitations such as resistance, cost of treatment, unavailability of drugs in rural areas and undesirable side effects necessitating the need to search for alternative approaches from natural sources including vegetables, honey and probiotics amongst others. These could form the basis of novel low cost, efficient, large-scale and alternative/complementary solutions with minimal side effects to decrease or eradicate?H. pylori?infections in the future.
机译：幽门螺杆菌是一种革兰氏阴性，微需氧螺旋或能动杆，它感染了全世界约一半的人口，在发展中国家的患病率很高。它是胃炎，消化性溃疡疾病，胃萎缩和B细胞粘膜相关淋巴样组织（MALT）淋巴瘤发展的重要病因。幽门螺杆菌感染是导致发病和死亡的重要原因，对全世界的医疗保健系统构成了重大负担。发展中国家感染的高流行归因于不良的社会经济地位和卫生条件，以及对抗生素的耐药性增加的趋势。抗菌化学疗法（两种抗生素和质子泵抑制剂）用于治疗？H。幽门螺杆菌感染已成为解决这些感染的最重要手段。然而，抗微生物疗法存在许多固有的局限性，例如抗药性，治疗成本，农村地区药物的缺乏和不良副作用，因此有必要从包括蔬菜，蜂蜜和益生菌在内的自然资源中寻找替代方法。这些可以构成新颖的低成本，高效，大规模，替代/补充解决方案的基础，并且具有减少或消除H的最小副作用。将来会发生幽门螺杆菌感染。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号