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首页> 外文期刊>African Journal of Biotechnology >Allelic and genotypic frequencies of ASIP and MC1R genes in four West African sheep populations
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Allelic and genotypic frequencies of ASIP and MC1R genes in four West African sheep populations

机译：西非四个绵羊种群中ASIP和MC1R基因的等位基因和基因型频率

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In West Africa, consumers pay a major attention on the coat colour of the sheep due to religious and cultural reasons. White coated?individuals reach?selling prices up to three-fold higher than black coated sheep.?The aim of this study was to ascertain the genotypic and allelic frequencies of?MC1R?and?ASIP?genes in order to assesspossible implementation of breeding programmes focusing on the increase of the white coated sheep frequencies.?A total of 113 individuals?belonging to three Burkina Faso sheep breeds (Burkina-Sahel, Djallonké and Mossi) and one Niger sheep breed (Touareg) were genotyped for the?MC1R?and?ASIP?genes.?The wild allele of the?ASIPgene (Awt; 54.30%) was the most frequent in the four West African sheep, particularly in Burkina-Sahel (85%) and Touareg breeds (80%). The dominant black ED?allele was not identified in Burkina-Sahel and Touareg. Most of the analysed individuals were homozygous for wild?MC1R?allele (E+/E+) with 100, 73.5, 59 and 100% frequency in Burkina-Sahel, Djallonké, Mossi and Touareg, respectively. The Awt/Awt?was the most frequent genotype on the?ASIP?gene in the four West African breeds (80.53%). No individuals were homozygous for the deletion (allele Adel). Although, no routine methods for detection of the genetic basis of the recessive black coat colour patterns can be easily implemented, the current results suggest the feasibility of a selection programme aiming at decreasing the frequencies of the dominant black ED?allele in Burkina Faso sheep breeds.
机译：在西非，由于宗教和文化原因，消费者主要关注绵羊的皮毛颜色。白皮个体的售价高达黑皮绵羊的三倍。这项研究的目的是确定“ MC1R”和“ ASIP”基因的基因型和等位基因频率，以评估可能实施的育种计划对MC1R基因型进行了分型，共113个个体，分别属于三个布基纳法索绵羊品种（布基纳-萨赫勒，Djallonké和Mossi）和一个尼日尔绵羊品种（途锐）。 “ ASIP”基因。“ ASIP”基因的野生等位基因（Awt; 54.30％）在四只西非绵羊中最为常见，特别是在布基纳-萨赫勒（85％）和途锐（80％）品种中。布基纳-萨赫勒地区和途锐地区未发现主要的黑色ED？等位基因。分析的大多数个体在布基纳-萨赫勒，迪亚隆克，莫西和图阿雷格的野生型MC1Rα等位基因（E + / E +）的纯合率分别为100、73.5、59和100％。 Awt / Awt？是西非四个品种中“ ASIP”基因上最常见的基因型（80.53％）。没有个体是纯合缺失的（等位基因Adel）。尽管无法轻易实施常规方法来检测隐性黑皮毛颜色模式的遗传基础，但目前的结果表明，旨在降低布基纳法索绵羊品种中主要黑色ED等位基因频率的选择方案的可行性。 。

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