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首页> 外文期刊>African Journal of Biotechnology >Screening of natural extracts for their antibacterial activity against different enteric pathogens isolated from soil, water and rotten fruit samples
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Screening of natural extracts for their antibacterial activity against different enteric pathogens isolated from soil, water and rotten fruit samples

机译：天然提取物对从土壤，水和腐烂水果样品中分离出来的不同肠道病原体的抗菌活性的筛选

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Different bacterial strains were isolated from soil, water and rotten fruit samples, and biochemically characterized as?Shigella, Pseudomonas, Escherichia coli, Klebsiellaand?Proteus.?Unhygienic environment (for example, contaminated food, water and air) are the most common habitats of these pathogens. Mostly, all are involved?in endemic breakouts causing urinary tract and gastro-intestinal infections. The antibacterial activity of four concentrations of natural crude extracts of medicinal plants namelyAllium sativum?(garlic),?Nigella sativa?(black cumin),?Trigonella foenum-graecum(fenugreek),?Ficus carica?(fig),?Azadirachta indica?(Indian lilac) and honey was determined against a total of ten isolated organisms by well plate method. Test organisms were found to be more sensitive to aqueous extract of bulb of?A. sativum,seeds of?Nigella sativa?and honey. The antibacterial activity of crude extract was comparable with ciprofloxacin and ceftriaxone, commonly used antibiotics for the treatment of infections in adults and children, respectively. It was observed from the studies that most of the test strains were resistant to the antibiotics used especially against ceftriaxone. Due to the emergence of drug resistant microorganisms, it is a need to search out more effective antimicrobial agents to cure the disease. Our studies suggest that aqueous crude extract of medicinally important plants and honey could be the alternative of the antibiotic to cure the diseases.
机译：从土壤，水和腐烂的水果样品中分离出不同的细菌菌株，其生化特性为：志贺氏菌，假单胞菌，大肠杆菌，克雷伯菌和变形杆菌。不卫生的环境（例如，受污染的食物，水和空气）是这些病原体。大多数情况下，所有这些都与地方性爆发有关，导致泌尿道和胃肠道感染。四种浓度的药用植物天然粗提取物的抗菌活性分别为大蒜，大蒜，黑胡椒，小木瓜，无花果和无花果。通过孔板法针对总共十种分离的生物体（印度丁香）和蜂蜜进行了测定。发现受试生物对？A鳞茎的水提物更敏感。朴素，“ Nigella sativa”和蜂蜜的种子。粗提物的抗菌活性可与环丙沙星和头孢曲松（分别用于成人和儿童感染的常用抗生素）相媲美。从研究中观察到，大多数测试菌株对所使用的抗生素具有抗性，尤其是针对头孢曲松。由于抗药性微生物的出现，需要寻找更有效的抗微生物剂来治愈该疾病。我们的研究表明，对医学有重要意义的植物和蜂蜜的粗提取物可以替代抗生素来治愈疾病。

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