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In vitro antifungal activity of Argemone ochroleuca Sweet latex against some pathogenic fungi

机译:och草乳胶对某些病原真菌的体外抗真菌活性

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The?in vitro?antifungal activities of crude latex of?Argemone ochroleuca?Sweet against four clinical isolates of?Candida?(Candida albicans, Candida glabrata, Candida kruseiand?Candida tropicalis)?and six isolates of plant pathogenic fungi?(Alternaria alternate,Drechslera halodes,?Fusarium oxysporum,?Macrophomina phaseolina, Pythium ultimum?and?Rhizoctoina solani)?were assessed using well diffusion method.?The chemical compounds of the hexan extract of?A. ochroleuca?latex were investigated using Perkin-Elmer Gas chromatography-Mass spectrometry. The latex of?A. ochroleuca?showed antifungal activity against?D. halodes?(10.60 mm)?and?Candidaspp.?(15.06 to 20.16 mm). GC-MS analysis of the hexan extract of?A. ochroleuca?latex revealed that the latex contains?diethyl phthalate?(81.57%),?6-Nitro-imidazo(1,2-a)pyridine?compound (8.833%),?cyclohexasiloxane, dodecamethyl- (5.607%),?4-(2,2-Dimethyl-6-methylenecyclohexylidene)-3-methylbutan-2-one?compound (2.410%) and cycloheptasiloxane, tetradecamethyl- (1.574%).?These findings indicate that the latex of?A. ochroleuca?could be a good source of antifungal agent against?D. halodes?andCandida?spp. and the?phytocomponents present in the latex could be used against fungal pathogens.
机译:甜Arg草粗制乳胶对四种临床分离的念珠菌(白色念珠菌,光滑念珠菌,克鲁斯氏念珠菌和热带念珠菌)和六种植物病原真菌分离株的体外抑真菌活性。用孔扩散法评估了德氏硬藻,尖孢镰刀菌,菜豆巨噬菌,终极腐霉和茄形假单胞菌。用Perkin-Elmer气相色谱-质谱法研究了草胶乳。 A.的乳胶och草显示出对?D的抗真菌活性。卤化物(10.60 mm)和Candidaspp。(15.06至20.16 mm)。用GC-MS分析?A的六边形萃取物。 och色胶乳显示该胶乳包含邻苯二甲酸二乙酯(81.57%),6-硝基咪唑并(1,2-a)吡啶化合物(8.833%),环环硅氧烷,十二甲基-(5.607%)、? 4 -(2,2-二甲基-6-亚甲基环己叉基)-3-甲基丁烷-2-酮化合物(2.410%)和环庚硅氧烷十四甲基-(1.574%)。这些发现表明αA胶乳。 och草可能是抗真菌药的良好来源。卤化物和念珠菌属。乳胶中的植物成分可用于抵抗真菌病原体。

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