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Chemical compositions and antimicrobial activity of twig essential oils from three Xylopia (Annonaceae) species

机译:三种木犀科(Annonaceae)枝杈精油的化学成分和抑菌活性

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The chemical composition of twig essential oils of Xylopia malayana, Xylopia elliptica and Xylopia fusca were analyzed using GC and GCMS. Both X. malayana (12.9%) and X. fusca (11.8%) twig oils contained spathulenol as the major constituent while X. elliptica twig oil was found to be rich in terpinen-4-ol (11.9%). The antimicrobial activities of the essential oils were evaluated against six gram positive bacteria, two gram negative bacteria and yeast by using the broth microdilution method. The twig oil of X. elliptica at a concentration ranging from 156 to 625 μg/ml was found to be active against all bacterial and yeast strains tested. Both X. malayana and X. fusca twig oils demonstrated weak activity toward all microorganisms tested with the MIC value of 5000 μg/ml. Gram negative bacteria’s, Pseudomonas aeruginosa and Escherichia coli seemed to be resistant to the essential oils tested. α-Pinene showed moderate to strong inhibitory effect against all the microorganism strains tested with the MIC value ranging from 325 to 2500 μg/ml, as compared to the other standard compounds which showed weak inhibitory even at the highest concentrations used. This finding demonstrated that the twig oil of X. elliptica possesses antimicrobial activity which may be useful and potential ingredient in the production of health care products.
机译:用GC和GCMS分析了马来西亚木瓜,椭圆形木瓜和木香的树枝精油的化学成分。马拉雅假单胞菌(X. malayana)(12.9%)和福氏假单胞菌(X. fusca(11.8%))的枝条油均以芦荟烯醇为主要成分,而椭圆形枝杈油则富含萜品四醇(11.9%)。使用肉汤微稀释法评估了精油对6克阳性细菌,2克阴性细菌和酵母的抗菌活性。已发现浓度为156至625μg/ ml的椭圆形沙棘的树枝油对所有测试的细菌和酵母菌株均具有活性。马拉雅假单胞菌油和树枝状假单胞菌油均显示出对所有测试微生物的活性较弱,MIC值为5000μg/ ml。革兰氏阴性菌,铜绿假单胞菌和大肠杆菌似乎对所测试的精油具有抗性。与其他标准化合物相比,α-P烯对所有测试的微生物菌株均显示出中等至强的抑制作用,MIC值在325至2500μg/ ml范围内,即使在所使用的最高浓度下,其抑制作用也很弱。这一发现表明,椭圆形雪松的树枝油具有抗微生物活性,这可能是保健产品生产中有用和潜在的成分。

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