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首页> 外文期刊>African Journal of Biotechnology >RNA interference: A novel tool for plant disease management
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RNA interference: A novel tool for plant disease management

机译：RNA干扰：一种用于植物病害管理的新工具

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Plant diseases pose a huge threat to crop production globally. Variations in their genomes cause selection to favor those who can survive pesticides and?Bacillus thuringiensis?(Bt)?crops. Though plant breeding has been the classical means of manipulating the plant genome to develop resistant cultivar for controlling plant diseases, the advent of genetic engineering provides an entirely new approach being pursued to render plants resistant to fungi, bacteria, viruses and nematodes. RNA interference (RNAi) technology has emerged to be a promising therapeutic weapon to mitigate the inherent risks such as the use of a specific transgene, marker gene, or gene control sequences associated with development of traditional transgenics. Silencing specific genes by RNAi is a desirable natural solution to this problem as disease resistant transgenic plants can be produced within a regulatory framework. Recent studies have been successful in producing potent silencing effects by using target double-stranded RNAs through an effective vector system. Transgenic plants expressing RNAi vectors, as well as, dsRNA containing crop sprays have been successful for efficient control of plant pathogens affecting economically important crop species. The present paper discusses strategies and applications of this novel technology in plant disease management for sustainable agriculture production.
机译：植物病害对全球农作物生产构成巨大威胁。基因组的变异使选择更加适合那些能够在农药和苏云金芽孢杆菌（Bt）作物中存活的人。尽管植物育种一直是操纵植物基因组以开发抗病品种来控制植物病害的经典方法，但是基因工程的出现提供了一种全新的方法来使植物对真菌，细菌，病毒和线虫具有抗性。 RNA干扰（RNAi）技术已经成为缓解潜在风险（例如使用特定转基因，标记基因或与传统转基因技术发展相关的基因控制序列）的有前途的治疗武器。 RNAi使特定基因沉默是解决该问题的理想自然方法，因为可以在调控框架内生产抗病性转基因植物。最近的研究已经成功地通过有效的载体系统使用靶标双链RNA产生了强大的沉默效果。表达RNAi载体的转基因植物以及含dsRNA的农作物喷雾剂已经成功地有效控制了影响经济上重要的农作物的植物病原体。本文讨论了该新技术在可持续农业生产的植物病害管理中的策略和应用。

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