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首页> 外文期刊>African Journal of Biotechnology >Isolation, purification and effects of hypoglycemic functional polysaccharides from Inonotus obliquus
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Isolation, purification and effects of hypoglycemic functional polysaccharides from Inonotus obliquus

机译：斜纹夜蛾低血糖功能多糖的分离纯化及作用

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Inonotus obliquus?is generally used for the treatment of diseases such as cancers, angiocardiopathy and diabetes. However, few studies are available on its functional components. The objective of this study?was?to isolate and purify hypoglycemic functional polysaccharides from?I. obliquus?(HPIO) and study their hypoglycemic activities.?I. obliquus?powder was used to obtain crude polysaccharides at room temperature (HPIO-R) and at high temperature (HPIO-H) using diethylaminoethyl cellulose?(DEAE)?cellulose -52 column chromatography for purification. Streptozotocin?(STZ)-induced hyperglycemic mice were used to evaluate the?in vivoantihyperglycemic and antilipidperoxidative effects of HPIOs at each eluted level. The results show that HPIO was a uniform compound and HPIO (0.2 mol/L NaCl) had antihyperglycemic effects and regulated lipid metabolism.
机译：Inonotus obliquus？通常用于治疗疾病，例如癌症，血管性心脏病和糖尿病。但是，关于其功能成分的研究很少。这项研究的目的是从I中分离和纯化降血糖功能多糖。并研究其降血糖活性。使用二乙氨基乙基纤维素（DEAE）-纤维素-52柱色谱法纯化，在室温（HPIO-R）和高温（HPIO-H）下使用斜粉得到粗多糖。链脲佐菌素（STZ）诱导的高血糖小鼠用于评估HPIOs在每种洗脱水平下的体内抗高血糖和抗脂质过氧化作用。结果表明，HPIO是均匀的化合物，HPIO（0.2 mol / L NaCl）具有降血糖作用和调节脂质代谢。

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