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Antimicrobial and antioxidant activities of the plant Heliotropium strigosum

机译:植物Heliotropium strigosum的抗菌和抗氧化活性

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Heliotropium strigosum?is an important medicinal plant and?belongs to the Boraginaceae family. Traditionally, this plant is used as laxative and diuretic. The juice of the plant is used to treat gum boils, sore eyes and also as a cure for stings of nettles, insects and snake bites. The current study was carried out to evaluate the medicinal properties of this plant. The plant was collected from Malakand, Pakistan. It was dried in shade and crushed into powder. The shade dried plant powder was macerated for 15 days. A crude extract and ethyl acetate, n-hexane, chloroform and aqueous fractions were obtained. The crude extract and fractions were screened for antibacterial, antifungal and antioxidant properties. The plant showed excellent antimicrobial activity. Chloroform and n-hexane fractions inhibited the growth of all four fungal strains that were used in the antifungal assays. Crude extract showed antifungal activity against all fungal strains except?Aspergillus flavus.?The aqueous and ethyl acetate fractions had no antifungal activity. The plant exhibited excellent antibacterial activity against?Pseudomonas aeruginosa?andStaphylococcus epidermidis, moderate activity against?methicillin resistantStaphylococcus aureus?(MRSA) and?Bacillus subtillus?but was inactive againstEscherichia coli?and?Klebsiella pneumonia. The plant showed excellent diphenyl picryl hydrazine (DPPH) scavenging activity. Antioxidant activity was shown by ethyl acetate, n-hexane and aqueous fractions. Crude extract and chloroform fractions were lacking in DPPH scavenging activity.
机译:Striosumium strigosum是一种重要的药用植物,属于紫草科。传统上,这种植物被用作泻药和利尿剂。该植物的汁液用于治疗口香糖,眼睛疼痛以及荨麻,昆虫和蛇咬伤的治疗。进行了当前的研究以评价该植物的药用特性。该植物采自巴基斯坦马拉坎德。将其在阴凉处干燥并粉碎成粉末。将阴凉干燥的植物粉末浸软15天。获得粗提取物和乙酸乙酯,正己烷,氯仿和含水部分。筛选粗提物和馏分的抗菌,抗真菌和抗氧化性能。该植物显示出优异的抗微生物活性。三氯甲烷和正己烷馏分抑制了用于抗真菌测定的所有四种真菌菌株的生长。粗提物对除黄曲霉外的所有真菌菌株均显示出抗真菌活性。水溶液和乙酸乙酯级分均无抗真菌活性。该植物对铜绿假单胞菌和表皮葡萄球菌具有优异的抗菌活性,对耐甲氧西林的金黄色葡萄球菌(MRSA)和枯草芽孢杆菌具有中等活性,但对大肠杆菌和克雷伯氏菌肺炎则无活性。该植物显示出优异的二苯基苦基肼(DPPH)清除活性。抗氧化剂活性通过乙酸乙酯,正己烷和水性馏分显示。粗提物和氯仿馏分缺乏DPPH清除活性。

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