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Immunomodulatory effects of orally administered aqueous extract from Eupolyphaga sinensis Walker

机译:口服大戟(Eupolyphaga sinensis Walker)水提取物的免疫调节作用

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This paper reported the immunnodulation tests of?Eupolyphaga sinensis?Walker in immunity. Mice were fed with?E. sinensis?water-decoction at a dose of 1.89, 3.78 and 7.56 g/kg/d for 4 weeks, then their immune function was studied. The results of the effects of?E. sinensis?water-decoction on spleen index, thymus index and carbon expurgation experiments of mice, indicated that?E. sinensis?did not affect visceral index, but enhanced observably carbon expurgatory index and phagocytic index.?E. sinensis?water-decoction could stimulate response of delayed hypersensitivity. The proliferation of concanavalin A (ConA)-induced mitogenic reponse for spleen lymphocyte was also increased. The amount of hemolytic antibody in mice serum increased when compared with those of the control group.E. sinensis?can enhance immunce function of mice. Therefore?E. sinensis?has immunnodulation function which could be developed and utilized as health food resource.
机译:本文报道了中华大E游走动物的免疫调节试验。给小鼠喂食?分别以1.89、3.78和7.56 g / kg / d的剂量水煎4周,然后研究其免疫功能。 E的影响结果。中华水煎液对小鼠脾脏指数,胸腺指数和碳清除实验的影响表明,E。中华绒螯蟹对内脏指数没有影响,但可观察到的碳排泄指数和吞噬指数明显提高。中华水煎液能刺激迟发型超敏反应。伴刀豆球蛋白A(ConA)诱导的脾淋巴细胞有丝分裂反应的增殖也增加了。与对照组相比,小鼠血清中的溶血抗体量增加。中华can可以增强小鼠的免疫功能。因此?中华绒螯蟹具有免疫调节功能,可作为保健食品资源开发利用。

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