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首页> 外文期刊>African Journal of Biotechnology >Passive- and active-cigarette smoking: Effects on the levels of antioxidant vitamins, immunoglobulin classes and acute phase reactants
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Passive- and active-cigarette smoking: Effects on the levels of antioxidant vitamins, immunoglobulin classes and acute phase reactants

机译：被动和主动吸烟：对抗氧化剂维生素，免疫球蛋白类别和急性期反应物水平的影响

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The levels of plasma immunoglobulin classes (IgG, A and M) and acute phase proteins?(α 2-macroglobulin (A2MG), C-reactive protein (CRP))?were determined using single radial immunodiffusion method. Also,?determined in the plasma of the subjects were antioxidant vitamins (vitamins C and E) using spectrophotometric method. The participants were 30 subjects who had never smoked and not exposed to cigarette smoke (non smokers), 30 who had smoked at least 15 cigarettes per day for at least five years (active smokers) and 30 who had been exposed to cigarette smoke at least 2 cigarette/day on ≥5 days/wk for at least 5 years (passive smokers). Plasma levels of IgG, IgM, CRP and A2MG were significantly raised (p<0.05), while vitamins C and E (p<0.05) were significantly reduced in active smokers when compared with the controls. The plasma levels of CRP and A2MG were significantly raised (p<0.05), while vitamins C and E were significantly reduced (p<0.05) in passive smokers when compared with the controls. The levels of CRP and antioxidant vitamins were similar in active and passive smokers. This study suggested that,?exposure to passive as well as active cigarette smoking cause’s inflammation as well as vitamin deficiency.
机译：采用单次放射免疫扩散法测定血浆免疫球蛋白类别（IgG，A和M）和急性期蛋白（α2-巨球蛋白（A2MG），C反应蛋白（CRP））的水平。此外，使用分光光度法测定受试者血浆中的抗氧化剂维生素（维生素C和E）。参与者为30名从未吸烟且未接触过香烟烟雾的受试者（非吸烟者），30名每天至少吸烟15年至少五年（活跃吸烟者）和30名至少接触香烟烟雾的受试者。每周至少5天（每周至少2天）每天吸烟2次（被动吸烟者）。与正常吸烟者相比，血浆中IgG，IgM，CRP和A2MG的血浆水平显着升高（p <0.05），而维生素C和E（p <0.05）则显着降低。与对照组相比，被动吸烟者的血浆CRP和A2MG水平显着升高（p <0.05），而维生素C和E显着降低（p <0.05）。主动和被动吸烟者的CRP和抗氧化剂维生素水平相似。这项研究表明，暴露于被动吸烟和主动吸烟会导致炎症和维生素缺乏症。

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