首页> 外文期刊>African Journal of Biotechnology >Susceptibility of imipenem-resistant Pseudomonas aeruginosa to flavonoid glycosides of date palm (Phoenix dactylifera L.) tamar growing in Al Madinah, Saudi Arabia
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Susceptibility of imipenem-resistant Pseudomonas aeruginosa to flavonoid glycosides of date palm (Phoenix dactylifera L.) tamar growing in Al Madinah, Saudi Arabia

机译:耐亚胺培南的铜绿假单胞菌对在沙特阿拉伯麦地那生长的枣椰树黄酮类黄酮的敏感性

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摘要

The fruits of the date palm (Phoenix dactylifera?L.) are consumed throughout the world and are an important part of the diet in the Middle East. Dates at tamar stage contain a wide array of flavones, but little is known about the antimicrobial of flavonoid glycosides compounds in dates. In this study, we evaluated the antimicrobial of flavonoid glycosides extracted from the date fruits grown in Al Madinah, Saudi Arabia at full ripe stage against imipenem-resistant?P. aeruginosa?(IRP). A chloroform fraction prepared from the date showed potent inhibitory activity against IRP. The active compounds were elucidated to be quercetin, luteolin, and apigenin based on their spectral analysis. Flavonoid glycosides showed significant antibacterial activities against IRP. These compounds represent novel leads, and future studies may allow the development of a pharmacologically acceptable antimicrobial agent or class of agents.
机译:椰枣(Phoenix dactylifera?L。)的果实在世界范围内食用,是中东饮食中的重要组成部分。添马舰期的枣中含有各种各样的黄酮,但对枣中的类黄酮糖苷类化合物的抗菌作用知之甚少。在这项研究中,我们评估了在完全成熟阶段从沙特阿拉伯麦地那(Al Madinah)生长的枣果实中提取的类黄酮糖苷对亚胺培南的抗药性。铜绿(IRP)。从那时起制备的氯仿馏分显示出对IRP的有效抑制活性。根据它们的光谱分析,将活性化合物阐明为槲皮素,木犀草素和芹菜素。黄酮苷显示出对IRP的显着抗菌活性。这些化合物代表了新的线索,未来的研究可能允许开发可药用的抗微生物剂或一类药物。

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