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首页> 外文期刊>African Journal of Biotechnology >Infant formula as a substrate for bifidogenesis: An in vitro investigation
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Infant formula as a substrate for bifidogenesis: An in vitro investigation

机译：婴儿配方奶粉作为双歧发生的底物：一项体外研究

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摘要

Six commercially available infant formulas (IF) without added prebiotic, were investigated as substrates for the growth of bifidobacteria isolated from the feces of 3 day old babies. This investigation tracked, during 48 h, the microbiological and biochemical changes in prepared infant formula meals, caused by the action of bifidobacteria, isolated from babies’ feces. Pancreatin digestion preceded inoculation of the bifidobacteria biomass. The reference substrate was mature breast milk. This investigation showed?important differences in bifidogenic effect between individual infant formulas and mature breast milk. In relation to dry biomass from the mature breast milk, dry biomass obtained in individual infant formulas ranged from 71.4% (IF-1) to 34.6% (IF-6).?The results showed?that, with the similar declared nutritive and biological characteristics, there are important differences between individual infant formulas.?The results obtained showed that, an??in vitrobifidogenic index test which covers tracking of microbiological and biochemical changes should be developed as a usefull tool in determining the suitability of infant formulas and it should be one of the first steps before clinical investigations.
机译：研究了六种不添加益生元的市售婴儿配方食品（IF）作为从3日龄婴儿的粪便中分离出来的双歧杆菌生长的底物。这项调查追踪了在48小时内从婴儿粪便中分离出的双歧杆菌的作用引起的婴儿配方奶粉的微生物学和生化变化。胰酶消化先于双歧杆菌生物质的接种。参考底物是成熟母乳。这项研究表明，婴儿配方奶粉和成熟母乳之间的双歧化作用有重要差异。对于来自成熟母乳的干生物质，在各个婴儿配方食品中获得的干生物质在71.4％（IF-1）至34.6％（IF-6）之间。结果表明，具有相似的营养价值和生物学价值。其特征表明，各个婴儿配方食品之间存在重要差异。获得的结果表明，应建立涵盖微生物学和生化变化追踪的体外双生指数测试，作为确定婴儿配方食品是否适用的有用工具。成为临床研究之前的第一步。

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