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Probing the evolutionary history of epigenetic mechanisms: what can we learn from marine diatoms

机译:探索表观遗传机制的进化历史:我们可以从海洋硅藻中学到什么

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Recent progress made on epigenetic studies revealed the conservation of epigenetic features in deep diverse branching species including Stramenopiles, plants and animals. This suggests their fundamental role in shaping species genomes across different evolutionary time scales. Diatoms are a highly successful and diverse group of phytoplankton with a fossil record of about 190 million years ago. They are distantly related from other super-groups of Eukaryotes and have retained some of the epigenetic features found in mammals and plants suggesting their ancient origin. Phaeodactylum tricornutum and Thalassiosira pseudonana , pennate and centric diatoms, respectively, emerged as model species to address questions on the evolution of epigenetic phenomena such as what has been lost, retained or has evolved in contemporary species. In the present work, we will discuss how the study of non-model or emerging model organisms, such as diatoms, helps understand the evolutionary history of epigenetic mechanisms with a particular focus on DNA methylation and histone modifications.
机译:表观遗传学研究的最新进展表明,在深层多样的分支物种中,包括Stramenopiles,植物和动物,表观遗传学特征得到了保护。这表明它们在不同进化时间尺度上塑造物种基因组中的基本作用。硅藻是一种非常成功且种类繁多的浮游植物,有大约1.9亿年前的化石记录。它们与真核生物的其他超群有密切的联系,并保留了哺乳动物和植物中发现的一些表观遗传学特征,表明它们的古老起源。三角藻和假硅藻分别为三角藻和中心硅藻,它们作为模型物种出现,以解决表观遗传现象的进化问题,例如在现代物种中丢失,保留或进化的现象。在当前的工作中,我们将讨论对非模型或新兴模型生物(例如硅藻)的研究如何帮助理解表观遗传机制的进化历史,并特别关注DNA甲基化和组蛋白修饰。

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