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A Pilot Community-Based Study on Association of Khat (Catha edulis) Chewing Practice with Psychosis in Yemen

机译:基于也门的叶绿素(Catha edulis)咀嚼行为与精神病联系的一项基于社区的试验研究

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Community-based studies on association of khat (Catha edulis) chewing practice with psychological problems among the ethnic users in Yemen have been strongly recommended. The present study was aimed to investigate the association of this practice with stress, sleep disturbances, and anorexia in Dhamar area which is a major source of khat in Arabian Peninsula. A cross-sectional study with a pre-tested questionnaire was carried out among 148 khat users and 150 non-users of khat. The psychological health outcomes (stress, sleep disturbances, and anorexia) were measured by self-assessment method. The estimated risks to predict the probability that participants would develop stress, sleep disturbances, and anorexia according to their khat chewing were examined using the Poisson regression model incorporating the robust estimator. Association of sleep disturbances and anorexia with stress weas also evaluated. The findings of the present study showed that stress, sleep disturbances, and anorexia were found to be increased significantly (P < 0.001) by 8.97, 9.28, and 7.28 times among the khat users, respectively. Accordingly, sleep disturbances and anorexia were significantly associated with stress (PR = 3.03; P < 0.001, PR = 2.33; P < 0.001, respectively). The results of this survey increase the need for attention among the regarded professionals about this harmful habit that can defect present and future of Yemeni people dramatically. However, more longitudinal researches pertaining to the contributory causal relationship of khat with psychosis are particularly needed.
机译:强烈建议在也门的族裔使用者中进行基于茶的咀嚼行为与心理问题相关性的社区研究。本研究旨在调查这种习俗与压力,睡眠障碍和厌食症之间的关系,而后者是阿拉伯半岛卡塔叶的主要来源。在148个卡塔叶使用者和150个非卡塔叶使用者中进行了带有预先测试问卷的横断面研究。心理健康结局(压力,睡眠障碍和厌食症)通过自我评估方法进行测量。使用结合了鲁棒估计量的Poisson回归模型检查了估计风险,以预测参与者根据其卡特咀嚼产生压力,睡眠障碍和厌食的可能性。还评估了睡眠障碍和厌食症与压力的关系。本研究的结果表明,在卡塔叶使用者中,压力,睡眠障碍和厌食症分别显着增加(P <0.001),分别为8.97、9.28和7.28倍。因此,睡眠障碍和厌食症与压力显着相关(分别为PR = 3.03; P <0.001; PR = 2.33; P <0.001)。这项调查的结果增加了敬业的专业人员对这种有害习惯的关注,这种有害习惯可能会严重破坏也门人民的现在和未来。然而,特别需要关于卡塔叶与精神病的因果关系的更深入的研究。

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