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首页> 外文期刊>American Journal of Psychiatry and Neuroscience >The Degree of Cognitive Impairment in Patients with Lacunar Stroke Depending on the Hemispheric Lateralization of the Lesion
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The Degree of Cognitive Impairment in Patients with Lacunar Stroke Depending on the Hemispheric Lateralization of the Lesion

机译：腔隙性脑卒中患者的认知障碍程度取决于病变的半球侧支

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The most susceptible to vascular dementia persons with lesions of small cerebral vessels. This variant of the pathology is characterized by subacute course and pathologic basis is diffuse changes in the white matter of the cerebral hemispheres and lacunar infarctions, in most cases - multiple. That is why the appearance of lacunar infarcts associated with step-progression of the disease. However, not in all cases, there is a significant cognitive defect even in a lacunary condition. The aim of the study was to identify cognitive impairment in patients with lacunar stroke, depending on hemispheric lateralization of the lesion. We observed and surveyed 70 patients (mean age 60.2 + 6.3) suffered the lacunar stroke with hemispheric lateralization of the lesion. In this work, we used the Mini-Mental State Examination (MMSE) and Montreal scale assessment of cognitive functions (MoCA), the Saint Louis University Mental Status Examination (SLUMS), which have been developed as a tool to identify and assess the severity of cognitive functions in general practice. Comparative analysis of cognitive impairment on the stage of the disease in the control group showed that in general, patients suffered lacunar stroke level of violations was significantly higher than the control group (p≤0.01). Cognitive function in right lacunar stroke corresponded moderate cognitive impairment and the restoration of the neurological defect in the dynamics were less expressed and are not complete. Cognitive impairment in the left hemisphere lacunar stroke had a mild degree of cognitive impairment and restoration of disturbed functions is progressing at a faster pace, about what speak reliable indicators of the late recovery period (p≤0.05). The differences in cognitive disorders at different focus lateralization underlie the clinical features and determine the nature and pace of the recovery of lost functions. Mild cognitive impairment in the left-hand lacunar stroke is a favorable prognostic factor in terms of the recovery of lost functions.
机译：最易患血管性痴呆的人脑小血管病变。这种病理变化的特征是亚急性病程，病理基础是大多数情况下脑半球和腔隙性脑梗死的白质呈弥漫性变化。这就是为什么腔隙性梗塞的出现与疾病的逐步进展有关的原因。但是，并非在所有情况下，即使在潜伏状态下也存在明显的认知缺陷。该研究的目的是根据腔内半球病变程度，识别腔隙性脑卒中患者的认知障碍。我们观察并调查了70名患者（平均年龄60.2 + 6.3），他们患有腔隙性脑卒中，病变半球偏侧。在这项工作中，我们使用了迷你精神状态检查（MMSE）和蒙特利尔认知功能量表评估（MoCA），圣路易斯大学心理状态考试（SLUMS），这些工具已被开发为识别和评估严重程度的工具在一般实践中的认知功能。对照组对疾病阶段认知障碍的比较分析表明，总体而言，患有腔隙性脑卒中的患者违规水平明显高于对照组（p≤0.01）。右腔隙性脑卒中的认知功能相应于中度认知障碍，动力学中神经系统缺损的恢复较少表达且不完整。左半球腔隙性脑卒中的认知障碍轻度认知障碍，功能障碍的恢复以更快的速度进展，这可以说是恢复后期的可靠指标（p≤0.05）。不同侧重点的认知障碍的差异是临床特征的基础，并决定丧失功能恢复的性质和步伐。就恢复功能丧失而言，左侧腔隙性脑卒中的轻度认知障碍是一个有利的预后因素。

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