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首页> 外文期刊>American Journal of PharmTech Research >Effectiveness of different extracts of cocoa powder on plasma glucose and lipid profile in alloxan-induced diabetes mellitus rats.
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Effectiveness of different extracts of cocoa powder on plasma glucose and lipid profile in alloxan-induced diabetes mellitus rats.

机译：可可粉不同提取物对四氧嘧啶诱发的糖尿病大鼠血浆葡萄糖和脂质分布的影响。

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ABSTRACT The use of different solvents to extract plant materials is to obtain component of utmost activity for the management of various disease conditions. Cocoa powder was subjected to different menstruum (aqueous, ethanol, n-hexane and chloroform) to remove inert materials and obtain pure active components whose effect was determined. Diabetes was induced in forty female Albino rats divided randomly into five groups, each consisting of eight rats, using 120mg/kg body weight alloxan. Different extracts of the powder were administered orally for twenty one days at a dose of 200mg/kg each except in the diabetic untreated group. Fasting blood sample was collected from the tail vein daily to determine the blood glucose concentration. On 22nd day, fasting blood samples were collected from all the rats for lipid profile estimation. Results showed a significant decrease (P
机译：摘要使用不同的溶剂提取植物材料是为了获得用于各种疾病状况管理的最大活性成分。使可可粉经受不同的月经（水溶液，乙醇，正己烷和氯仿）以去除惰性物质，并获得确定其作用的纯净活性成分。用120mg / kg体重的四氧嘧啶在40只雌性白化病大鼠中诱发糖尿病，将其随机分为五组，每组八只大鼠。除糖尿病未治疗组外，以200mg / kg的剂量口服不同粉末的提取物二十一次。每天从尾静脉收集空腹血样以确定血糖浓度。在第22天，从所有大鼠中收集空腹血液样品用于脂质分布估计。结果显示显著下降（P

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