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首页> 外文期刊>Annals of microbiology >The prevalence of antibiotic resistance genes among Aeromonas species in aquatic environments
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The prevalence of antibiotic resistance genes among Aeromonas species in aquatic environments

机译：水生环境中气单胞菌中抗生素抗性基因的流行

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The global rise in antimicrobial resistance (AMR) among bacteria causing infectious diseases is well documented, and the associated risks for human health are well known. There is much less research on AMR with regard to environmental strains, both opportunistic and pathogenic ones. The genus Aeromonas is widely distributed in the environment and causes many variable diseases in fish and humans. Infections in humans are predominantly caused by Aeromonas veronii, A. hydrophila and A. caviae (A. punctata) in a form of bacteremia, gastroenteritis or even septicaemia in immunocompetent and immunocompromised individuals. Different groups of antibiotics are used in the treatment, but studies indicate that fluoroquinolones and cefotaxime are the most efficient. A disturbing consequence of antibiotic overuse is an increasing number of detection of various antibiotic resistance genes (ARG) within this genus. The water environment is one of the major modes of transmission of resistant bacteria from animals to humans, and, thus, the dissemination of antibiotic resistance genes, particularly those located in mobile genetic elements (MGE) occurs in such as plasmids and transposons. This review summarizes recently published information on the type, distribution, and transmission of ARG by MGE, widespread in Aeromonas strains living in various aquatic environments, including wastewater, natural water, aquaculture and urban drinking water. The data available indicate that the opportunistic pathogens like Aeromonas spp. might serve as important vectors of ARG for clinically relevant pathogens present in such bodies of water .
机译：引起感染性疾病的细菌中抗微生物药耐药性（AMR）的全球上升已得到充分证明，并且对人类健康的相关风险也是众所周知的。关于机会性和致病性环境菌株的AMR研究很少。气单胞菌属广泛分布于环境中，并在鱼类和人类中引起多种疾病。在人类中，感染主要是由Vereroii气单胞菌，嗜水气单胞菌和ca.caviae（punctata）引起的，它们是具有免疫能力和免疫功能低下的个体的菌血症，胃肠炎甚至败血症。治疗中使用了不同种类的抗生素，但是研究表明，氟喹诺酮类和头孢噻肟是最有效的。抗生素过度使用的一个令人不安的后果是，该属中各种抗生素抗性基因（ARG）的检测数量不断增加。水环境是抗性细菌从动物向人类传播的主要方式之一，因此，抗生素抗性基因的传播，特别是位于移动遗传元件（MGE）中的那些，发生在质粒和转座子中。这篇综述总结了最近发表的有关MGE的ARG的类型，分布和传播的信息，这些信息广泛存在于生活在各种水生环境中的气单胞菌菌株中，包括废水，天然水，水产养殖和城市饮用水。可用数据表明机会病原体如气单胞菌。可能作为这些水域中临床相关病原体的ARG的重要载体。

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