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首页> 外文期刊>Annals of Maxillofacial Surgery >Clonidine: An adjuvant to adrenaline in local anesthesia for third molar surgery
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Clonidine: An adjuvant to adrenaline in local anesthesia for third molar surgery

机译：可乐定：用于第三磨牙手术的局部麻醉中肾上腺素的佐剂

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Purpose: The aim of the study is to compare the efficacy of anesthesia and hemodynamic parameters of clonidine and epinephrine in lignocaine for lower third molar surgery. Materials and Methods: Thirty healthy controls with impacted mandibular third molar were randomly selected from both sexes between the age group of 20–47 years. Patients were divided equally into two groups: Group I (Adrenaline group) and Group II (Clonidine group). Patients received 2.5 ml of 2% lignocaine with adrenaline (12.5 μg/ml) in Adrenaline group and 2.5 ml of 2% lignocaine with clonidine (15 μg/ml) in Clonidine group. Hemodynamic parameters (heart rate, systolic blood pressure [SBP], diastolic blood pressure [DBP], and mean arterial pressure [MAP]) were recorded preoperatively, intraoperatively, and postoperatively. The onset of anesthesia and duration of anesthesia were recorded using pinprick test for both groups. Postoperatively, patients were evaluated for pain experience by the visual analog scale and verbal rating scale. Results: Lignocaine with clonidine intraoperatively and postoperatively decreases SBP and DBP and MAP compared to lignocaine with adrenaline. There was no significant difference in the onset and duration of anesthesia in both the groups. There was a statistically significant difference seen in the visual analog scale, but no statistically significant difference was seen in the verbal rating scale. Conclusion: Clonidine has similar efficacy as that of adrenaline with better hemodynamic parameters and can be used as an alternative to adrenaline for third molar surgeries.
机译：目的：本研究的目的是比较利尼卡因用于下颌第三磨牙手术的麻醉效果和可乐定和肾上腺素的血流动力学参数。材料与方法：从20-47岁年龄段的男女中随机选择30例患下颌第三磨牙的健康对照。将患者平均分为两组：第一组（肾上腺素组）和第二组（可乐定组）。肾上腺素组患者接受2.5 ml 2％的利多卡因和肾上腺素（12.5μg/ ml），可乐定组接受2.5 ml 2％的利古卡因和可乐定（15μg/ ml）。术前，术中和术后记录血流动力学参数（心率，收缩压[SBP]，舒张压[DBP]和平均动脉压[MAP]）。两组均使用pinprick试验记录麻醉的开始时间和麻醉时间。术后，通过视觉模拟量表和口头评定量表评估患者的疼痛经历。结果：与含肾上腺素的利多卡因相比，利多卡因术中和术后加可乐定可降低SBP，DBP和MAP。两组的麻醉开始时间和持续时间均无显着差异。在视觉类比量表中有统计上的显着差异，但在语言评分表中没有统计上的显着差异。结论：可乐定具有与肾上腺素相似的功效，并且具有更好的血液动力学参数，可作为第三磨牙手术的替代肾上腺素。

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