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Comparison of haemoglobin level between high altitude people and low altitude people

机译:高海拔人群和低海拔人群血红蛋白水平的比较

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Background : Hemoglobin is the iron holding and oxygen carrying protein found inside the red blood cells. Studies have been done on Hb level variations in gender, race and region but no comparative study on different altitude effects in Pakistan is reported. Comparison of Hemoglobin level between people living at high altitude and low altitude was done in this study. Samples from district Skardu Gilgit-Baltistan, Pakistan were used as high-altitude samples and samples from district Lahore, Pakistan were utilized as low altitude samples. Samples were obtained from those people who don’t have any haemoglobinopathies. Methods: 50 blood samples were collected for this study; 25 individuals were from low altitude level and 25 of high-altitude level. Estimation of hemoglobin concentration was done by Cyanmethemoglobin method to compare the individuals HB from low altitude with high altitude. Results: All the blood samples were properly analyzed, and the results extracted from the samples, living at low altitude were compared with those living at high altitude. Mean and standard deviation values were calculated, and they found to be different for both populations, people at high altitude and the people living at low altitude. 25 residents of high altitude showed following results of hemoglobin: mean=15.0 and SD=0.632. On the other hand, 25 individuals of low altitude revealed these results: mean=14.53 and SD=0.633. Conclusion: There was a significant difference in Hb level in blood at high altitude (7500 feet) and low altitude (711 feet from sea level) P=0.004.
机译:背景:血红蛋白是在红细胞内发现的铁和载氧蛋白。关于性别,种族和地区血红蛋白水平变化的研究已经完成,但没有关于巴基斯坦不同海拔影响的比较研究报告。本研究对高海拔和低海拔人群的血红蛋白水平进行了比较。来自巴基斯坦Skardu Gilgit-Baltistan地区的样本被用作高空样本,来自巴基斯坦Lahore地区的样本被用作低空样本。样本是从没有任何血红蛋白病的人那里获得的。方法:收集50份血液样本进行研究。低海拔地区有25个人,高海拔地区有25个人。用氰化高铁血红蛋白法估算血红蛋白浓度,以比较低海拔和高海拔人群的HB。结果:对所有血液样本进行了适当的分析,并将从低海拔地区和高海拔地区抽取的血液样本进行了比较。计算出平均值和标准偏差值,发现它们在人口,高海拔人群和低海拔人群中都不同。 25位高海拔居民表现出以下血红蛋白结果:平均值= 15.0和SD = 0.632。另一方面,有25个低海拔的个体显示了以下结果:平均值= 14.5,SD = 0.633。结论:高海拔(7500英尺)和低海拔(距海平面711英尺)的血液中Hb水平存在显着差异P = 0.004。

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