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首页> 外文期刊>Archives of Applied Science Research >In vitro antibacterial studies of some transition metal complexes of schiff base derived from 2-aminophenol and furan-2-carbaldehyde
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In vitro antibacterial studies of some transition metal complexes of schiff base derived from 2-aminophenol and furan-2-carbaldehyde

机译:某些2-氨基苯酚和呋喃-2-甲醛衍生的席夫碱过渡金属配合物的体外抗菌研究

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A novel Schiff-base ligand and its Ni(II) & Cu(II) complexes were synthesized and well characterized by elemental analyses and spectral studies. Physical and analytical data suggest that the Schiff base acts as tridentate ligand towards metal ions via azomethine-N, deprotonated-O of 2-aminophenol and O-atom of furan moiety. The synthesized ligand, along with its metal complexes were screened for their in-vitro antibacterial activity against four bacterial pathogens (E. coli, Bacillus subtilis, Staphylococcus aureus and P. vulgareous ). The results of these studies revealed that the free ligand and its metal complexes showed significant antibacterial potency.
机译:合成了一种新型的席夫碱配体及其Ni(II)和Cu(II)配合物,并通过元素分析和光谱研究对其进行了很好的表征。物理和分析数据表明,席夫碱通过偶氮甲碱-N,2-氨基苯酚的去质子-O和呋喃部分的O-原子作为金属离子的三齿配体。筛选合成的配体及其金属配合物对四种细菌病原体(大肠杆菌,枯草芽孢杆菌,金黄色葡萄球菌和寻常性毕赤酵母)的体外抗菌活性。这些研究的结果表明,游离配体及其金属配合物表现出显着的抗菌效力。

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