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An overview of available Hypoglycemic Triterpenoids and Saponins to cure Diabetes mellitus

机译：可用降糖三萜和皂苷治疗糖尿病的概述

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Diabetes mellitus is a condition when excess amount of sugar is excreted out in the urine. It is probably caused due to hyperglycemia; when body fails to produce sufficient amount of insulin which may utilize or help to store these excessive carbohydrates. When a body does not produce sufficient insulin or to help utilize carbohydrates, it results in the accumulation of unutilized sugar in the blood, the condition is termed as hyperglycemia whereas the condition of passing off the excess sugar in the urine is known as diabetes mellitus. The excretion of sugar makes a profound effect on health that may lead to disability and death. According to some studies, it may cause myocardial infarction, cardiovascular disorders and terminal nephritis. These complications are reported to be the most important causes of mortality and the principal cause of irreversible blindness. There are hundreds of millions of patients around the world suffering from this disease and the number is spreading with an alarming rate. Such a condition has inspired the therapists to develop the methods which help in controlling this malaise. In this article, we have summarized some of hypoglycemic agents from natural sources especially from plants. Since there is a vast number of plants, which are reported to be utilized traditionally in the crude form for diabetes cure in the past. This article is meant to mention only the hypoglycemic ingredients of triterpenoids origin. This information can be helpful in getting new and more effective drugs in future by utilizing unexplored plants which are reported in the literature to possess hypoglycemic activity. This current review is comprised of the relevant work done up to the year 2007 based on search from Google.
机译：糖尿病是尿液中过量糖分排出的一种状况。它可能是由于高血糖引起的;当身体无法产生足够的胰岛素时，可能会利用或帮助储存这些过量的碳水化合物。当人体无法产生足够的胰岛素或无法帮助利用碳水化合物时，会导致血液中未利用的糖蓄积，这种情况被称为高血糖症，而尿液中多余糖分掉的状况被称为糖尿病。糖的排泄对健康产生深远影响，可能导致残疾和死亡。根据一些研究，它可能引起心肌梗塞，心血管疾病和终末性肾炎。据报道，这些并发症是导致死亡的最重要原因，也是不可逆性失明的主要原因。世界上有数亿患者患有这种疾病，并且数量正以惊人的速度扩散。这种情况激发了治疗师开发有助于控制这种不适的方法。在本文中，我们总结了一些天然来源的降血糖药，尤其是植物。由于存在大量植物，据报道过去以传统形式将其粗制用于糖尿病治疗。本文旨在仅提及三萜类化合物的降血糖成分。该信息可通过利用文献中报道的具有降血糖活性的未开发植物来帮助将来获得新的和更有效的药物。本次审查包括根据Google搜索在2007年之前完成的相关工作。

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